User:Mr. Ibrahem/Cefadroxil
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| Clinical data | |
|---|---|
| Trade names | Duricef |
| Other names | Cephadroxil |
| AHFS/Drugs.com | Monograph |
| MedlinePlus | a682730 |
| Routes of administration | By mouth |
| Drug class | Antibiotic (1st generation cephalosporin)[1] |
| Legal status | |
| Legal status |
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| Pharmacokinetic data | |
| Protein binding | plasma protein |
| Metabolism | unknown |
| Elimination half-life | 1.5 hours |
| Identifiers | |
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| Chemical and physical data | |
| Formula | C16H17N3O5S |
| Molar mass | 363.39 g·mol−1 |
| 3D model (JSmol) | |
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  (what is this?) (verify) | |
Cefadroxil, sold under the brand name Duricef, is an antibiotic typically used to treat bacterial infections of the skin and soft tissue and urinary tract.[2][3] It may be used for gram-positive and gram-negativeinfections.[2] It is taken by mouth as a capsule.[2] If kidney problems, the dose may need adjusting.[2]
Common side effects include indigestion and a sore tongue.[2] Less likely is the occurrence of fungal infections, and rarely it may cause joint pains, tiredness, liver problems, difficulty sleeping, and anxiety.[2] Use during pregnancy or breastfeeding does not appear to harm the baby.[2] It is a first-generation cephalosporin.[1] It prevents the last stage of formation of the bacterial cell wall.[4]
Cefadroxil was patented in 1967 and approved for medical use in 1978.[5] It is available as a generic medication.[2] In the United Kingdom, a course of treatment costs the NHS around £20, as of 2021.[2] This amount in the United States is about 10 USD.[6]
References[edit]
- ^ a b Beauduy, Camille E.; Winston, Lisa G. (2020). "43. Beta-lactam and other cell wall - & membrane - active antibiotics". In Katzung, Bertram G.; Trevor, Anthony J. (eds.). Basic and Clinical Pharmacology (15th ed.). New York: McGraw-Hill. p. 830. ISBN 978-1-260-45231-0. Archived from the original on 2021-10-10. Retrieved 2021-12-01.
- ^ a b c d e f g h i j k l "5. Infection". British National Formulary (BNF) (82 ed.). London: BMJ Group and the Pharmaceutical Press. September 2021 – March 2022. p. 557. ISBN 978-0-85711-413-6.
{{cite book}}: CS1 maint: date format (link) - ^ "A - Z Drug List from Drugs.com: Cefadroxil". Drugs.com. American Society of Health-System Pharmacists. Archived from the original on 24 May 2016. Retrieved 20 November 2021.
- ^ Jain, Mayur S.; Barhate, Shashikant D.; Gayakwad, Bhushan P. (22 March 2018). "Cefadroxil: A Review of Analytical Methods". Asian Journal of Pharmaceutical Analysis. 8 (1): 58–61. doi:10.5958/2231-5675.2018.00011.X. Archived from the original on 2021-04-19. Retrieved 2021-12-01.
- ^ Fischer J, Ganellin CR (2006). Analogue-based Drug Discovery. John Wiley & Sons. p. 493. ISBN 9783527607495. Archived from the original on 2017-09-10. Retrieved 2020-12-31.
- ^ "Cefadroxil Prices, Coupons & Savings Tips - GoodRx". GoodRx. Retrieved 30 December 2021.