User:Mr. Ibrahem/Indapamide

Mr. Ibrahem/Indapamide
Clinical data
AHFS/Drugs.com	Monograph
MedlinePlus	a684062
Pregnancy; category	AU: C; ;
Routes of; administration	By mouth
Drug class	Thiazide-like diuretic
Legal status
Legal status	UK: POM (Prescription only);
Pharmacokinetic data
Protein binding	71–79%
Metabolism	Liver
Elimination half-life	14–18 hours
Identifiers
	IUPAC name 4-chloro-N-(2-methyl-2,3-dihydroindol-1-yl)-3-sulfamoyl-benzamide;
Chemical and physical data
Formula	C16H16ClN3O3S
Molar mass	365.83 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O=S(=O)(N)c1c(Cl)ccc(c1)C(=O)NN3c2ccccc2CC3C;
	InChI InChI=1S/C16H16ClN3O3S/c1-10-8-11-4-2-3-5-14(11)20(10)19-16(21)12-6-7-13(17)15(9-12)24(18,22)23/h2-7,9-10H,8H2,1H3,(H,19,21)(H2,18,22,23) ; Key:NDDAHWYSQHTHNT-UHFFFAOYSA-N ;
	(verify)

Indapamide is a medication used to treat high blood pressure and swelling due to heart failure or other causes.^[1] It is a second line treatment for high blood pressure in pregnancy.^[1] It is taken by mouth.^[1] It may be used with other blood pressure medications.^[1]

Common side effects include low potassium, headache, dizziness, tiredness, numbness, and anxiety.^[1] Other side effects may include low sodium, rash, gout, and high blood sugar.^[1] It is a thiazide-like diuretic.^[1]

Indapamide was patented in 1968 and approved for medical use in 1977.^[3] It is available as a generic medication.^[2] In the United Kingdom it costs the NHS about £3.40 a month as of 2021.^[2] In the United States this amount costs about 4 USD per month.^[4] A combination medication with perindopril is also available.^[2]

References[edit]

^ ^a ^b ^c ^d ^e ^f ^g ^h ⁱ ^j "Indapamide Monograph for Professionals". Drugs.com. Archived from the original on 10 January 2021. Retrieved 26 November 2021.
^ ^a ^b ^c ^d BNF 81: March-September 2021. BMJ Group and the Pharmaceutical Press. 2021. p. 181. ISBN 978-0857114105.
^ Fischer J, Ganellin CR (2006). Analogue-based Drug Discovery. John Wiley & Sons. p. 457. ISBN 9783527607495. Archived from the original on 2021-08-28. Retrieved 2021-01-16.
^ "Indapamide Prices, Coupons & Savings Tips - GoodRx". GoodRx. Archived from the original on 31 August 2016. Retrieved 26 November 2021.

[AHFS2021-1] ^ ^a ^b ^c ^d ^e ^f ^g ^h ⁱ ^j "Indapamide Monograph for Professionals". Drugs.com. Archived from the original on 10 January 2021. Retrieved 26 November 2021.

[BNF81-2] BNF 81: March-September 2021. BMJ Group and the Pharmaceutical Press. 2021. p. 181. ISBN 978-0857114105.

[Fis2006-3] Fischer J, Ganellin CR (2006). Analogue-based Drug Discovery. John Wiley & Sons. p. 457. ISBN 9783527607495. Archived from the original on 2021-08-28. Retrieved 2021-01-16.

[4] "Indapamide Prices, Coupons & Savings Tips - GoodRx". GoodRx. Archived from the original on 31 August 2016. Retrieved 26 November 2021.

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