User:Mr. Ibrahem/Lasmiditan

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Mr. Ibrahem/Lasmiditan
Clinical data
Trade namesReyvow
Other namesCOL-144
AHFS/Drugs.comMonograph
MedlinePlusa620015
License data
Routes of
administration
By mouth
Drug class5-HT1F receptor activator[1]
Legal status
Legal status
Identifiers
  • 2,4,6-Trifluoro-N-[6-[(1-methyl-4-piperidinyl)carbonyl]-2-pyridinyl]benzamide
Chemical and physical data
FormulaC19H18F3N3O2
Molar mass377.367 g·mol−1
3D model (JSmol)
  • CN1CCC(CC1)C(=O)C2=NC(=CC=C2)NC(=O)C3=C(C=C(C=C3F)F)F
  • InChI=1S/C19H18F3N3O2/c1-25-7-5-11(6-8-25)18(26)15-3-2-4-16(23-15)24-19(27)17-13(21)9-12(20)10-14(17)22/h2-4,9-11H,5-8H2,1H3,(H,23,24,27) ☒N
  • Key:XEDHVZKDSYZQBF-UHFFFAOYSA-N ☒N
 ☒NcheckY (what is this?)  (verify)

Lasmiditan, sold under the brand name Reyvow, is a medication used to treat migraine headaches.[3] It is not useful for prevention.[3] It is taken by mouth.[3] It is less effective and more expensive than sumatriptan.[4]

Common side effects include dizziness, tiredness, and numbness.[1] Other side effects may include serotonin syndrome, medication overuse headaches, and poor coordination.[1] It has a low risk for misuse.[3] Safety in pregnancy is unclear.[3] It is a 5-HT1F receptor activator.[1]

Lasmiditan was approved for medical use in the United States in 2019.[3] In the United States it costs about 83 USD per 100 mg dose as of 2021.[5] It is not available in the United Kingdom or Europe as of 2021.[4]

References[edit]

  1. ^ a b c d e "Reyvow- lasmiditan tablet". DailyMed. 11 October 2019. Archived from the original on 25 November 2020. Retrieved 15 November 2019.
  2. ^ "2020 - Placement of Lasmiditan in Schedule V". DEA Diversion Control Division. 31 January 2020. Archived from the original on 31 January 2020. Retrieved 31 January 2020.
  3. ^ a b c d e f g h "Lasmiditan Monograph for Professionals". Drugs.com. Archived from the original on 23 January 2021. Retrieved 21 November 2021.
  4. ^ a b "Lasmiditan". SPS - Specialist Pharmacy Service. 30 December 2015. Archived from the original on 21 November 2021. Retrieved 21 November 2021.
  5. ^ "Reyvow Prices and Reyvow Coupons - GoodRx". GoodRx. Retrieved 21 November 2021.