User:Mr. Ibrahem/Macular degeneration

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Macular degeneration
Other namesAge-related macular degeneration
Picture of the back of the eye showing intermediate age-related macular degeneration
SpecialtyOphthalmology
SymptomsBlurred or no vision in the center of the visual field[1]
ComplicationsVisual hallucinations[1]
Usual onsetOlder people[1]
TypesEarly, intermediate, late[1]
CausesDamage to the macula of the retina[1]
Risk factorsGenetics, smoking[1]
Diagnostic methodEye examination[1]
PreventionExercising, eating well, not smoking[1]
TreatmentAnti-VEGF medication injected into the eye, laser coagulation, photodynamic therapy[1]
Frequency6.2 million (2015)[2]

Macular degeneration, also known as age-related macular degeneration (AMD or ARMD), is a medical condition which may result in blurred or no vision in the center of the visual field.[1] Early on there are often no symptoms.[1] Over time, however, some people experience a gradual worsening of vision that may affect one or both eyes.[1] While it does not result in complete blindness, loss of central vision can make it hard to recognize faces, drive, read, or perform other activities of daily life.[1] Visual hallucinations may also occur but these do not represent a mental illness.[1]

Macular degeneration typically occurs in older people.[1] Genetic factors and smoking also play a role.[1] It is due to damage to the macula of the retina.[1] Diagnosis is by a complete eye exam.[1] The severity is divided into early, intermediate, and late types.[1] The late type is additionally divided into "dry" and "wet" forms with the dry form making up 90% of cases.[1][3]

Preventive efforts include exercising, eating well, and not smoking.[1] There is no cure or treatment that returns vision already lost.[1] In the wet form, anti-VEGF medication injected into the eye or less commonly laser coagulation or photodynamic therapy may slow worsening.[1] Antioxidant vitamins and minerals do not appear to be useful for prevention.[4] However, dietary supplements may slow the progression in those who already have the disease.[5]

In 2015 it affected 6.2 million people globally.[2] In 2013 it was the fourth most common cause of blindness after cataracts, preterm birth, and glaucoma.[6] It most commonly occurs in people over the age of fifty and in the United States is the most common cause of vision loss in this age group.[1][3] About 0.4% of people between 50 and 60 have the disease, while it occurs in 0.7% of people 60 to 70, 2.3% of those 70 to 80, and nearly 12% of people over 80 years old.[3]

References[edit]

  1. ^ a b c d e f g h i j k l m n o p q r s t u v w x "Facts About Age-Related Macular Degeneration". National Eye Institute. June 2015. Archived from the original on 22 December 2015. Retrieved 21 December 2015.
  2. ^ a b GBD 2015 Disease and Injury Incidence and Prevalence Collaborators (October 2016). "Global, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015". The Lancet. 388 (10053): 1545–1602. doi:10.1016/S0140-6736(16)31678-6. PMC 5055577. PMID 27733282. {{cite journal}}: |author= has generic name (help)CS1 maint: numeric names: authors list (link)
  3. ^ a b c Mehta S (September 2015). "Age-Related Macular Degeneration". Primary Care. 42 (3): 377–91. doi:10.1016/j.pop.2015.05.009. PMID 26319344.
  4. ^ Evans JR, Lawrenson JG (July 2017). "Antioxidant vitamin and mineral supplements for preventing age-related macular degeneration". The Cochrane Database of Systematic Reviews. 7: CD000253. doi:10.1002/14651858.CD000253.pub4. PMC 6483250. PMID 28756617.
  5. ^ Evans JR, Lawrenson JG (July 2017). "Antioxidant vitamin and mineral supplements for slowing the progression of age-related macular degeneration". The Cochrane Database of Systematic Reviews. 7: CD000254. doi:10.1002/14651858.CD000254.pub4. PMC 6483465. PMID 28756618.
  6. ^ Vos, Theo; Barber, Ryan M.; Bell, Brad; Bertozzi-Villa, Amelia; Biryukov, Stan; Bolliger, Ian; Charlson, Fiona; Davis, Adrian; Degenhardt, Louisa; Dicker, Daniel; Duan, Leilei; Erskine, Holly; Feigin, Valery L.; Ferrari, Alize J.; Fitzmaurice, Christina; Fleming, Thomas; Graetz, Nicholas; Guinovart, Caterina; Haagsma, Juanita; Hansen, Gillian M.; Hanson, Sarah Wulf; Heuton, Kyle R.; Higashi, Hideki; Kassebaum, Nicholas; Kyu, Hmwe; Laurie, Evan; Liang, Xiofeng; Lofgren, Katherine; Lozano, Rafael; MacIntyre, Michael F. (August 2015). "Global, regional, and national incidence, prevalence, and years lived with disability for 301 acute and chronic diseases and injuries in 188 countries, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013". The Lancet. 386 (9995): 743–800. doi:10.1016/s0140-6736(15)60692-4. PMC 4561509. PMID 26063472. {{cite journal}}: Unknown parameter |displayauthors= ignored (|display-authors= suggested) (help)