User:Mr. Ibrahem/Mavacamten

Mr. Ibrahem/Mavacamten
Clinical data
Trade names	Camzyos
Other names	MYK-461
AHFS/Drugs.com	Monograph
License data	US DailyMed: Mavacamten;
Routes of; administration	By mouth
Drug class	Cardiac myosin inhibitor
Legal status
Legal status	AU: S4 (Prescription only); US: ℞-only;
Identifiers
	IUPAC name 6-[[(1S)-1-phenylethyl]amino]-3-propan-2-yl-1H-pyrimidine-2,4-dione;
Chemical and physical data
Formula	C15H19N3O2
Molar mass	273.336 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CC(C)N1C(=O)NC(N[C@@H](C)C2=CC=CC=C2)=CC1=O;
	InChI InChI=1S/C15H19N3O2/c1-10(2)18-14(19)9-13(17-15(18)20)16-11(3)12-7-5-4-6-8-12/h4-11,16H,1-3H3,(H,17,20)/t11-/m0/s1; Key:RLCLASQCAPXVLM-NSHDSACASA-N;

Mavacamten, sold under the brand name Camzyos, is a medication used to treat hypertrophic obstructive cardiomyopathy (HCOM).^[2] It is taken by mouth.^[2]

Common side effects include dizziness and syncope.^[2] Other side effects may include heart failure.^[2] Use in pregnancy may harm the baby.^[2] It is a cardiac myosin inhibitor.^[2]

Mavacamten was approved for medical use in the United States in 2022.^[2] It is not available in Europe or the United Kingdom as of 2022.^[3] In the United States a month of medication costs about 7,800 USD.^[4]

References[edit]

^ "Archive copy". Archived from the original on 2022-11-13. Retrieved 2022-11-29.{{cite web}}: CS1 maint: archived copy as title (link)
^ ^a ^b ^c ^d ^e ^f ^g ^h ⁱ ^j "Camzyos- mavacamten capsule, gelatin coated". DailyMed. 28 April 2022. Archived from the original on 3 July 2022. Retrieved 15 May 2022.
^ "Mavacamten". SPS - Specialist Pharmacy Service. 19 October 2018. Archived from the original on 24 June 2022. Retrieved 12 December 2022.
^ "Camzyos Prices, Coupons, Copay & Patient Assistance". Drugs.com. Archived from the original on 22 May 2023. Retrieved 12 December 2022.

[1] "Archive copy". Archived from the original on 2022-11-13. Retrieved 2022-11-29.{{cite web}}: CS1 maint: archived copy as title (link)

[PI2022-2] ^ ^a ^b ^c ^d ^e ^f ^g ^h ⁱ ^j "Camzyos- mavacamten capsule, gelatin coated". DailyMed. 28 April 2022. Archived from the original on 3 July 2022. Retrieved 15 May 2022.

[SPS022-3] "Mavacamten". SPS - Specialist Pharmacy Service. 19 October 2018. Archived from the original on 24 June 2022. Retrieved 12 December 2022.

[4] "Camzyos Prices, Coupons, Copay & Patient Assistance". Drugs.com. Archived from the original on 22 May 2023. Retrieved 12 December 2022.

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