User:Mr. Ibrahem/Platelet transfusion
 A bag of platelets | |
| Clinical data | |
|---|---|
| Other names | Platelet concentrate, platelet component |
Platelet transfusion, also known as platelet concentrate, is used to prevent or treat bleeding in people with either a low platelet count or poor platelet function.[2] Often this occurs in people receiving cancer chemotherapy.[2] Preventive transfusion is often done in those with platelet levels of less than 10 x 109/L.[3] In those who are bleeding transfusion is usually carried out at less than 50 x 109/L.[3] Blood group matching (ABO, RhD) is typically recommended before platelets are given.[3] Unmatched platelets, however, are often used due to the unavailability of matched platelets.[4] They are given by injection into a vein.[5]
Side effects can include allergic reactions such as anaphylaxis, infection, and lung injury.[3] Bacterial infections are relatively more common with platelets as they are stored at warmer temperatures.[3] Platelets can be produced either from whole blood or by apheresis.[2] They can be stored for up to five to seven days.[2]
Platelet transfusions came into medical use in the 1950s and 1960s.[2][6] It is on the World Health Organization's List of Essential Medicines.[7] In the United Kingdom it costs the NHS about £200 per unit.[8] Some versions of platelets have had the white blood cells partially removed or been gamma irradiated which have specific benefits for certain populations.[9]
References[edit]
- ^ "WHOCC - ATC/DDD Index". www.whocc.no. Archived from the original on 1 July 2021. Retrieved 14 September 2020.
- ^ a b c d e Hillyer, Christopher D. (2007). Blood Banking and Transfusion Medicine: Basic Principles & Practice. Elsevier Health Sciences. pp. 308–310. ISBN 978-0443069819. Archived from the original on 2017-01-12.
- ^ a b c d e Connell NT (December 2016). "Transfusion Medicine". Primary Care. 43 (4): 651–659. doi:10.1016/j.pop.2016.07.004. PMID 27866583.
- ^ Josephson CD, Castillejo MI, Grima K, Hillyer CD (February 2010). "ABO-mismatched platelet transfusions: strategies to mitigate patient exposure to naturally occurring hemolytic antibodies". Transfusion and Apheresis Science. 42 (1): 83–8. doi:10.1016/j.transci.2009.10.013. PMID 20034854.
- ^ Linton, Adrianne Dill (2015). Introduction to Medical-Surgical Nursing. Elsevier Health Sciences. p. 287. ISBN 9781455776412. Archived from the original on 2017-01-12.
- ^ Das PC, Smit-Sibinga CT, Halie MR (2012). Supportive therapy in haematology. Springer Science & Business Media. p. 190. ISBN 9781461325772. Archived from the original on 2017-01-10.
- ^ World Health Organization (2019). World Health Organization model list of essential medicines: 21st list 2019. Geneva: World Health Organization. hdl:10665/325771. WHO/MVP/EMP/IAU/2019.06. License: CC BY-NC-SA 3.0 IGO.
- ^ Yentis, Steven M.; Hirsch, Nicholas P.; Ip, James (2013). Anaesthesia and Intensive Care A–Z: An Encyclopedia of Principles and Practice. Elsevier Health Sciences. p. 147. ISBN 9780702053757. Archived from the original on 2017-01-12.
- ^ Hillyer, Christopher D. (2007). Blood Banking and Transfusion clinical Basic Principles & Practice. Elsevier Health Sciences. p. 320. ISBN 978-0443069819. Archived from the original on 2017-01-12.