User:Mr. Ibrahem/Polystyrene sulfonate

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Mr. Ibrahem/Polystyrene sulfonate
Clinical data
Trade namesSodium salt: Kayexalate, Kionex, Resonium A
Calcium salt: Calcium Resonium, Sorbisterit, Resikali
AHFS/Drugs.comMonograph
MedlinePlusa682108
Routes of
administration
By mouth, retention enema
Drug classCation exchange resin[1]
Legal status
Legal status
  • In general: ℞ (Prescription only)
Pharmacokinetic data
BioavailabilityNone
MetabolismNone
ExcretionFaeces (100%)
Identifiers
  • Poly(4-vinylbenzenesulfonic acid)
Chemical and physical data
Formula[C8H7SO3] n
 ☒NcheckY (what is this?)  (verify)

Polystyrene sulfonates are a group of medications used to treat high blood potassium.[1][2] Effects generally take hours to days.[1] It may be taken by mouth or used rectally.[1]

Common side effects include loss of appetite, gastrointestinal upset, constipation, and low blood calcium.[1] Serious side effects may include intestinal injury, electrolyte abnormalities, and heart failure.[1] It works as a cation exchange resin.[1]

Sodium polystyrene sulfonate was approved for medical use in the United States in 1958.[1] In the United States the sodium salt costs about 60 USD for 450 grams as of 2021.[3] In the United Kingdom this amount of the sodium salt costs about £81 while the calcium salt costs about £125.[2]

References[edit]

  1. ^ a b c d e f g h i j "Sodium Polystyrene Sulfonate Monograph for Professionals". Drugs.com. Archived from the original on 21 October 2020. Retrieved 25 October 2019.
  2. ^ a b BNF (80 ed.). BMJ Group and the Pharmaceutical Press. September 2020 – March 2021. p. 1117. ISBN 978-0-85711-369-6.{{cite book}}: CS1 maint: date format (link)
  3. ^ "Sodium polystyrene sulfonate Prices, Coupons & Patient Assistance Programs". Drugs.com. Archived from the original on 25 October 2019. Retrieved 12 October 2021.