User:Mr. Ibrahem/Polystyrene sulfonate
Clinical data | |
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Trade names | Sodium salt: Kayexalate, Kionex, Resonium A Calcium salt: Calcium Resonium, Sorbisterit, Resikali |
AHFS/Drugs.com | Monograph |
MedlinePlus | a682108 |
Routes of administration | By mouth, retention enema |
Drug class | Cation exchange resin[1] |
Legal status | |
Legal status |
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Pharmacokinetic data | |
Bioavailability | None |
Metabolism | None |
Excretion | Faeces (100%) |
Identifiers | |
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Chemical and physical data | |
Formula | [C8H7SO3−] n |
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Polystyrene sulfonates are a group of medications used to treat high blood potassium.[1][2] Effects generally take hours to days.[1] It may be taken by mouth or used rectally.[1]
Common side effects include loss of appetite, gastrointestinal upset, constipation, and low blood calcium.[1] Serious side effects may include intestinal injury, electrolyte abnormalities, and heart failure.[1] It works as a cation exchange resin.[1]
Sodium polystyrene sulfonate was approved for medical use in the United States in 1958.[1] In the United States the sodium salt costs about 60 USD for 450 grams as of 2021.[3] In the United Kingdom this amount of the sodium salt costs about £81 while the calcium salt costs about £125.[2]
References[edit]
- ^ a b c d e f g h i j "Sodium Polystyrene Sulfonate Monograph for Professionals". Drugs.com. Archived from the original on 21 October 2020. Retrieved 25 October 2019.
- ^ a b BNF (80 ed.). BMJ Group and the Pharmaceutical Press. September 2020 – March 2021. p. 1117. ISBN 978-0-85711-369-6.
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: CS1 maint: date format (link) - ^ "Sodium polystyrene sulfonate Prices, Coupons & Patient Assistance Programs". Drugs.com. Archived from the original on 25 October 2019. Retrieved 12 October 2021.