User talk:Johanndante/Bionumbers
Bionumbers is a collaborative community database of useful biological numbers. Users contribute various numbers (e.g., number of ribosomes in a cell, concentration of ions and metabolites, or generation times of organisms) as well as references and other relevant information.
Goal[edit]
Numbers are absolute and immutable entities. Biology is built on adaptation and flexibility. It is thus no surprise that concrete values for many biological properties are hard to find. Most quantitative properties in biology depend on the context or the method of measurement, the organism and the cell type. Yet it is clear that characteristic numbers and ranges are very useful tools to have available. The aim of the database is to be a repository for useful biological numbers, that gives a concrete value while supplying the relevant reference and comments that depict its domain of validity.[citation needed]
Interesting examples from BioNumbers[edit]
- Number of mRNAs in cell (total absolute number)
- Yeast - 15000 (BNID 100273)
- Escherichia coli - 1380 (BNID 100064)
- Number ATP to make 1 cell
- Escherichia coli - 55 billion (BNID 100178)
- Minimal generation time
- Vibrio natriegens - 9.8 minutes (BNID 100297)
- Mutation rate per genome per replication
- Escherichia coli - 0.0025 (BNID 100266)
References[edit]
Phillips R, Milo R. A feeling for the numbers in biology. Proc Natl Acad Sci U S A. 2009 Dec 14 PMID 20018695
Milo R, Jorgensen P, Moran U, Weber G, Springer M. BioNumbers--the database of key numbers in molecular and cell biology. Nucleic Acids Res. 2009 Oct 23. PMID 19854939
http://openwetware.org/wiki/BioNumbers