Wikipedia:USEP/Courses/JHU MolBio Ogg FA13/Group 84A

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Group 84A[edit]

This is a group page for the 410.602 Johns Hopkins Molecular Biology, section 84 course. This group will be working on the article TBD.

Use the talk page here to collaborate as a group, when learning to use and navigate Wikipedia, assessing articles, or for any other topic.

Use this page (not the talk page) for article assessments; rationale for selecting an article; etc (as specified in the milestone summary chart.

Please create a new section here for each of those assignments.

Initial article assessments from Apoptosis81[edit]

Article 1: Capping Enzyme[edit]

This article is essentially a stub article with a useful definition of what a capping enzyme is, but does not do much to expand and broadly cover the topic. This article contains very little to satisfy the criteria of a good article. Since it is essentially a definition of a capping enzyme and its function it is well written and neutral. However, it does not contain enough sources, is not broad, and contains no images. There is no discussion on the talk page regarding improving this page.

Some possible references for this article are:[edit]

Article 2: Transferase[edit]

This article is also a stub article. The article is basically a definition of a transferase, but is not particularly well written. Other than being neutral, this article fails at nearly all of the good article criteria. It is not broad in its scope, contains almost no references, and no images. Many of these criteria seem like they would be easy to improve as there is much information about these important enzymes that could be added. Since transferases are implicated in many different biological systems, the scope can be quite large. I tried to capture some sources that show this scope. There is no discussion on the talk pages in regards to improving this article.

Some possible references for this article are:[edit]

Initial article assessments from Pdholak1[edit]

Article 1: Biosynthesis[edit]

This article has been identified as a stub. Not only is there content missing, but it does not have enough citations to make it a valid article. It gives very vague information about an array of topics related to the subject of biosynthesis, but does not provide sufficient information about the topic for someone looking to gain a general understanding about it. Specific examples should be added. Some diagrams would also be helpful!

Some possible references for this article:[edit]

Article 2: Exoenzyme[edit]

This article is also a stub. It is not very well-written, lacking major details in the definition of the subject. The rest of the article is just a list of examples that link to other Wiki articles. An improvement for the article would be to provide brief descriptions for each of these examples to broaden its coverage of the topic. It does not provide any citations which should be fixed!

Some possible references for this article:[edit]

Rationale for Choosing Exoenzyme[edit]

Our group decided to use this article because it shows a lot of potential for improvement. This past week, this was one of the four articles we chose to evaluate, and thus we already have a starting point for how we may improve this article. The article is clearly a stub, and will provide us with the opportunity to make substantial contributions to its content. This topic is focused yet complex, making it possible to discuss it in depth without adding too much extra information. The article already provides links to other Wiki articles and highlights specific exoenzymes that can be used as focus points, providing us with a clear direction of how we may expand on this topic. Since the article is currently just a list of examples, necessary edits include adding a general definition of the topic and adding images to make the article easier to understand. To provide validity and maintain neutrality, citations and in-line citations must also be found and added. By adding the above edits, we hope to improve this article into one that will provide the reader with enough information to have a solid understanding of exoenzymes!

Unit 8 progress report[edit]

All contributions were prose (basic description and brief history with new sources).

Unit 10 progress report[edit]

Most new contributions were prose (examples of exoenzymes). Figures for the general description and some examples were also added.

Unit 12 progress report[edit]

New additions were mostly prose: Biotechnolical and industrial applications and trypsin example added. Figure for biodiesel reaction was added as well. Disambiguation of some wikilinks was also fixed during this unit.

Unit 14 progress report[edit]

Most of the new additions were prose: Function, Examples of Virulence Factors section, Bacterial Assays, and Bioremediation sections, as well as expansion of existing sections. Multiple images were also added: virulence factor examples, multiple image of assays, and bioremediation images. A special thanks to Adimart1, Jirwin1097, Aconch, WillPugarth, hnagy2, klortho, and Juanquina Thomas for their continued feedback that helped us enhance this article!

References[edit]

  1. ^ Shatkin, Aaron J.; Manley, James L. (1 October 2000). "The ends of the affair: Capping and polyadenylation". Nature Structural Biology. 7 (10): 838–842. doi:10.1038/79583. PMID 11017188. S2CID 188513.
  2. ^ Hirose, Yutaka; James L. Manley (2000). "RNA polymerase II and the integration of nuclear events". Genes and Development. 14 (12): 1415–1429. doi:10.1101/gad.14.12.1415. PMID 10859161. S2CID 43589702.
  3. ^ Walsh, Christopher (17 August 2000). "Molecular mechanisms that confer antibacterial drug resistance". Nature. 406 (6797): 775–781. Bibcode:2000Natur.406..775W. doi:10.1038/35021219. PMID 10963607. S2CID 4372465.
  4. ^ Chouchana, L.; Narjoz, C.; Beaune, P.; Loriot, M.-A.; Roblin, X. (1 January 2012). "Review article: the benefits of pharmacogenetics for improving thiopurine therapy in inflammatory bowel disease". Alimentary Pharmacology & Therapeutics. 35 (1): 15–36. doi:10.1111/j.1365-2036.2011.04905.x. PMID 22050052. S2CID 24066222.
  5. ^ Josephy, P. David (1 January 2010). "Genetic Variations in Human Glutathione Transferase Enzymes: Significance for Pharmacology and Toxicology". Human Genomics and Proteomics. 2010: 1–14. doi:10.4061/2010/876940. PMID 20981235.
  6. ^ Schön, A; Kannangara, CG; Gough, S; Söll, D (14 January 1988). "Protein biosynthesis in organelles requires misaminoacylation of tRNA". Nature. 331 (6152): 187–90. Bibcode:1988Natur.331..187S. doi:10.1038/331187a0. PMID 3340166. S2CID 4356899.
  7. ^ Clarke, SW (1987). "Management of mucus hypersecretion". European Journal of Respiratory Diseases. Supplement. 153: 136–44. PMID 3322858.
  8. ^ Johnson, HG; McNee, ML; Braughler, JM (December 1987). "Inhibitors of metal catalyzed lipid peroxidation reactions inhibit mucus secretion and 15 HETE levels in canine trachea". Prostaglandins, Leukotrienes, and Medicine. 30 (2–3): 123–32. doi:10.1016/0262-1746(87)90142-9. PMID 3122232.
  9. ^ Bhatia, M.S. (2009). Principles of microbiology (1. ed.). Delhi, India: Swastik Publishers & Distributors. pp. 225–228. ISBN 978-81-89981-27-3.
  10. ^ Goodsell, David (2006). "Alpha-amylase". Molecule of the Month. doi:10.2210/rcsb_pdb/mom_2006_2. Retrieved 9 October 2013.