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16S rRNA (guanine966-N2)-methyltransferase

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16S rRNA (guanine966-N2)-methyltransferase
Identifiers
EC no.2.1.1.171
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
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PMCarticles
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NCBIproteins

16S rRNA (guanine966-N2)-methyltransferase (EC 2.1.1.171, yhhF (gene), rsmD (gene), m2G966 methyltransferase) is an enzyme with systematic name S-adenosyl-L-methionine:16S rRNA (guanine966-N2)-methyltransferase.[1] This enzyme catalyses the following chemical reaction

S-adenosyl-L-methionine + guanine966 in 16S rRNA S-adenosyl-L-homocysteine + N2-methylguanine966 in 16S rRNA

The enzyme efficiently methylates guanine966 of the assembled 30S subunits in vitro.

References

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  1. ^ Lesnyak DV, Osipiuk J, Skarina T, Sergiev PV, Bogdanov AA, Edwards A, Savchenko A, Joachimiak A, Dontsova OA (February 2007). "Methyltransferase that modifies guanine 966 of the 16 S rRNA: functional identification and tertiary structure". The Journal of Biological Chemistry. 282 (8): 5880–7. doi:10.1074/jbc.m608214200. PMC 2885967. PMID 17189261.
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