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2-dehydro-3-deoxy-L-arabinonate dehydratase

From Wikipedia, the free encyclopedia
2-dehydro-3-deoxy-L-arabinonate dehydratase
Identifiers
EC no.4.2.1.43
CAS no.37263-10-8
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
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PMCarticles
PubMedarticles
NCBIproteins

The enzyme 2-dehydro-3-deoxy-L-arabinonate dehydratase (EC 4.2.1.43) catalyzes the chemical reaction

2-dehydro-3-deoxy-L-arabinonate 2,5-dioxopentanoate + H2O

This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is 2-dehydro-3-deoxy-L-arabinonate hydro-lyase (2,5-dioxopentanoate-forming). Other names in common use include 2-keto-3-deoxy-L-arabinonate dehydratase, and 2-dehydro-3-deoxy-L-arabinonate hydro-lyase. This enzyme participates in ascorbate and aldarate metabolism.

References

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  • Stoolmiller AC, Abeles RH (1966). "Formation of alpha-ketoglutaric semialdehyde from L-2-keto-3-deoxyarabonic acid and isolation of L-2-keto-3-deoxyarabonate dehydratase from Pseudomonas saccharophila". J. Biol. Chem. 241 (24): 5764–71. PMID 5954356.