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23S rRNA (guanine2069-N7)-methyltransferase

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23S rRNA (guanine2069-N7)-methyltransferase
Identifiers
EC no.2.1.1.264
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
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PMCarticles
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NCBIproteins

23S rRNA (guanine2069-N7)-methyltransferase (EC 2.1.1.264, rlmK (gene), 23S rRNA m7G2069 methyltransferase) is an enzyme with systematic name S-adenosyl-L-methionine:23S rRNA (guanine2069-N7)-methyltransferase.[1] This enzyme catalyses the following chemical reaction

S-adenosyl-L-methionine + guanine2069 in 23S rRNA S-adenosyl-L-homocysteine + N7-methylguanine2069 in 23S rRNA

The enzyme specifically methylates guanine2069 at position N7 in 23S rRNA.

References

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  1. ^ Kimura S, Ikeuchi Y, Kitahara K, Sakaguchi Y, Suzuki T, Suzuki T (May 2012). "Base methylations in the double-stranded RNA by a fused methyltransferase bearing unwinding activity". Nucleic Acids Research. 40 (9): 4071–85. doi:10.1093/nar/gkr1287. PMC 3351187. PMID 22210896.
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