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3-oxoadipate CoA-transferase

From Wikipedia, the free encyclopedia
3-oxoadipate CoA-transferase
Identifiers
EC no.2.8.3.6
CAS no.9026-16-8
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
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PMCarticles
PubMedarticles
NCBIproteins

In enzymology, a 3-oxoadipate CoA-transferase (EC 2.8.3.6) is an enzyme that catalyzes the chemical reaction

succinyl-CoA + 3-oxoadipate succinate + 3-oxoadipyl-CoA

Thus, the two substrates of this enzyme are succinyl-CoA and 3-oxoadipate, whereas its two products are succinate and 3-oxoadipyl-CoA.

This enzyme belongs to the family of transferases, specifically the CoA-transferases. The systematic name of this enzyme class is succinyl-CoA:3-oxoadipate CoA-transferase. Other names in common use include 3-oxoadipate coenzyme A-transferase, and 3-oxoadipate succinyl-CoA transferase. This enzyme participates in benzoate degradation via hydroxylation.

References

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  • KATAGIRI M, HAYAISHI O (1957). "Enzymatic degradation of beta-ketoadipic acid". J. Biol. Chem. 226 (1): 439–48. PMID 13428776.