Jump to content

6-Ketoprogesterone

From Wikipedia, the free encyclopedia
6-Ketoprogesterone
Names
IUPAC name
Pregn-4-ene-3,6,20-trione
Other names
6-Ketoprogesterone;6-Oxoprogesterone
Identifiers
3D model (JSmol)
ChemSpider
MeSH C111515
UNII
  • InChI=1S/C21H28O3/c1-12(22)15-4-5-16-14-11-19(24)18-10-13(23)6-8-21(18,3)17(14)7-9-20(15,16)2/h10,14-17H,4-9,11H2,1-3H3/t14-,15+,16-,17-,20+,21+/m0/s1
    Key: LASCNIPXMJNRGS-HGUQNLGYSA-N
  • InChI=1/C21H28O3/c1-12(22)15-4-5-16-14-11-19(24)18-10-13(23)6-8-21(18,3)17(14)7-9-20(15,16)2/h10,14-17H,4-9,11H2,1-3H3/t14-,15+,16-,17-,20+,21+/m0/s1
    Key: LASCNIPXMJNRGS-HGUQNLGYBS
  • O=C4\C=C3\C(=O)C[C@@H]1[C@H](CC[C@@]2([C@@H](C(=O)C)CC[C@@H]12)C)[C@@]3(C)CC4
Properties
C21H28O3
Molar mass 328.452 g·mol−1
Density 1.14 g/cm3
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

6-Ketoprogesterone is an orally active oxidized form of progesterone that contains a keto group at position-6.[1][non-primary source needed]

References

[edit]
  1. ^ Carlo, J; Pincus, G.; Carlo, J.; Romanoff, E. B. (March 1, 1956). "Isolation of an Unknown Substance and 6-Ketoprogesterone from Perfusates of Human Placentae". Endocrinology. 58 (3): 387–388. doi:10.1210/endo-58-3-387. PMID 13294088.

Further reading

[edit]

Paul B. Glickman, MD; Robert H. Palmer, MD; Attallah Kappas, MD (July 1964). "Steroid Fever And Inflammation". Arch Intern Med. 114 (1): 46–58. doi:10.1001/archinte.1964.03860070092009. PMID 14152129.