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ATG9B

From Wikipedia, the free encyclopedia
ATG9B
Identifiers
AliasesATG9B, APG9L2, NOS3AS, SONE, autophagy related 9B
External IDsOMIM: 612205; MGI: 2685420; HomoloGene: 72638; GeneCards: ATG9B; OMA:ATG9B - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001317056

NM_001002897

RefSeq (protein)

NP_001303985
NP_775952

NP_001002897

Location (UCSC)Chr 7: 151.01 – 151.02 MbChr 5: 24.59 – 24.6 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Autophagy related 9B is a protein that in humans is encoded by the ATG9B gene.[5]

Function

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This gene functions in the regulation of autophagy, a lysosomal degradation pathway. This gene also functions as an antisense transcript in the post-transcriptional regulation of the endothelial nitric oxide synthase 3 gene, which has 3' overlap with this gene on the opposite strand. Mutations in this gene and disruption of the autophagy process have been associated with multiple cancers. Alternative splicing results in multiple transcript variants.

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000181652Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000038295Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: Autophagy related 9B". Retrieved 2017-06-12.

Further reading

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.