Alain Viel
Alain Viel | |
|---|---|
| Born | France |
| Alma mater | Pierre and Marie Curie University |
| Known for | The Inner Life of the Cell |
| Partner | Robert Lue (d. 2020) |
| Scientific career | |
| Fields | Biochemistry, biology |
| Institutions | Harvard University |
| Doctoral advisor | Marc le Maire Daniel Branton |
Alain Viel is the director of Northwest Undergraduate Laboratories and senior lecturer in the Department of Molecular and Cellular Biology at Harvard University.[1]
Early life and education
[edit]Viel received a PhD in molecular and cellular biology of development in 1990 from Pierre and Marie Curie University in Paris, France (Paris VI) for a thesis "Les particules ribonucleoproteiques dans le oocytes de xenopus laevis. mise en place du systeme de synthese proteique" [2] and did postdoctoral work at Harvard University.[3]
Academic career
[edit]His main research have been on tumor suppressor hDlg which includes an in-depth characterization of the combinations of hDlg isoforms present in multiple tissues and cell lines to correlate the presence of specific alternatively spliced insertions with a specific function of this tumor suppressor. He also studies the perturbation of hDlg distribution in two skin disease: psoriasis, characterized by a hyper-proliferation of basal cells, and Darier's disease, characterized by blisters resulting from the loss of cell adhesion in the supra-basal layers.[4][5]
He is a founding member of BioVisions.[6]
Lectures
[edit]In 2015, Viel started to teach an online course MCB63X - Principles of Biochemistry with Rachelle Gaudet on edX.[7]
Publications
[edit]Books
[edit]Viel is a co-author of the book Biology: How Life Works. It is published by Macmillan Education and is the first project to develop three pillars: the text, the visual program, and the assessment at the same time.[8]
Multimedia
[edit]Viel is co-author of The Inner Life of the Cell,[9][10] an 8.5-minute 3D computer graphics animation illustrating the molecular mechanisms that occur when a white blood cell in the blood vessels of the human body is activated by inflammation (Leukocyte extravasation). It shows how a white blood cell rolls along the inner surface of the capillary, flattens out, and squeezes through the cells of the capillary wall to the site of inflammation where it contributes to the immune reaction.[11]
References
[edit]- ^ Instructor Profile: Alain Viel at edX
- ^ [1] WorldCat item listing
- ^ "Epernicus, Alain Viel". Archived from the original on 2009-07-03. Retrieved 2015-07-11.
- ^ "Profile at Department of Molecular and Cellular Biology, Harvard University". Archived from the original on 2015-07-12. Retrieved 2015-07-11.
- ^ Peter Reuell (10 September 2013). "Summer in the lab, Harvard Gagette". News.harvard.edu. Retrieved 2019-05-06.
- ^ "Macmillan Higher Education". Macmillanhighered.com. Retrieved 2019-05-06.
- ^ "edX bio". Edx.org. Retrieved 2019-05-06.
- ^ "Biology: How Life Works". Macmillanhighered.com. Retrieved 2019-05-06.
- ^ "animation The Inner Life of the Cell". Archived from the original on 2008-12-15. Retrieved 2019-05-06.
- ^ Marchant, Beth (2006-07-20). "Studio Daily". Studio Daily. Retrieved 2019-05-06.
- ^ "Lives of a Cell, the 3-D Version". Wired News. March 14, 2007. Retrieved 2015-06-12.
External links
[edit]- Webpage at Harvard University
- Northwest Teaching Laboratories
- MCB63X, Principles of Biochemistry, HarvardX, edX
- BioVisions** "The Inner Life of the Cell". Harvard University. Archived from the original on December 15, 2008., "Narrated version". Archived from the original on December 25, 2008.
- YouTube video
- The Inner Life of the Cell - Shockwave Flash Video (without narration)
- Extravasion Simplified cartoon version of the same process.
- David Bolinsky's Speech Presenting The Inner Life of the Cell