α-Methylhistamine
Appearance
(Redirected from Alpha-methylhistamine)
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Names | |
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IUPAC name
1-(3H-Imidazol-4-yl)propan-2-amine
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Systematic IUPAC name
1-(1H-Imidazol-4-yl)propan-2-amine[1] | |
Identifiers | |
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3D model (JSmol)
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ChEBI | |
ChEMBL | |
ChemSpider | |
MeSH | Alpha-methylhistamine |
PubChem CID
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CompTox Dashboard (EPA)
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Properties | |
C6H11N3 | |
Molar mass | 125.175 g·mol−1 |
log P | -0.346 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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α-Methylhistamine is a histamine agonist selective for the receptor subtype H3. It causes lowering of blood pressure and a decrease of heart rate in animal models.[2]
References
[edit]- ^ "Chemical Entities of Biological Interest (ChEBI)".
- ^ McLeod, RL; Gertner, SB; Hey, JA (1993). "Production by R-alpha-methylhistamine of a histamine H3 receptor-mediated decrease in basal vascular resistance in guinea-pigs". Br J Pharmacol. 110 (2): 553–558. doi:10.1111/j.1476-5381.1993.tb13846.x. PMC 2175947. PMID 7902173.