Azabon
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Formula | C14H20N2O2S |
Molar mass | 280.386 |
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Azabon is a central nervous system stimulant of the sulfonamide class[1] that is also used as a nootropic.[2] As it is a sulpha drug, care must be taken during administration, and certain individuals must avoid azabon altogether to prevent an allergic reaction. Despite being a sulfonamide, azabon has poor antibacterial potency, although this decreased activity is common among other benzenesulfonamides with two substituents on N1. Azabon is synthesized from 3-azabicyclo-[2.2.2]nonane, which is itself prepared by pyrolysis of aliphatic diamine.[3]
See also
[edit]References
[edit]- ^ WO 2011089215, Vetter D, Rau H, "Dipeptide-based prodrug linkers for aromatic amine-containing drugs", published 28 July 2011, assigned to Ascendis Pharma AS
- ^ Mao F, Ni W, Xu X, Wang H, Wang J, Ji M, Li J (January 2016). "Chemical Structure-Related Drug-Like Criteria of Global Approved Drugs". Molecules. 21 (1): 75. doi:10.3390/molecules21010075. PMC 6273477. PMID 26771590.
- ^ Lednicer D, Mitscher LA (1980). The Organic Chemistry of Drug Synthesis (PDF). Vol. 2. Wiley Interscience. p. 115. ISBN 0-471-04392-3.