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B3GNT2

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B3GNT2
Identifiers
AliasesB3GNT2, B3GN-T2, B3GNT, B3GNT-2, B3GNT1, BETA3GNT, BGNT2, BGnT-2, 3-Gn-T1, 3-Gn-T2, beta-1, beta3Gn-T1, beta3Gn-T2, UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
External IDsOMIM: 605581; MGI: 1889505; HomoloGene: 4797; GeneCards: B3GNT2; OMA:B3GNT2 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_006577
NM_033252
NM_001319075
NM_018554

NM_001169114
NM_016888

RefSeq (protein)

NP_001306004
NP_006568

NP_001162585
NP_058584

Location (UCSC)Chr 2: 62.2 – 62.22 MbChr 11: 22.71 – 22.81 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 is an enzyme that in humans is encoded by the B3GNT2 gene.[5][6][7]

This gene encodes a member of the beta-1,3-N-acetylglucosaminyltransferase family. This enzyme is a type II transmembrane protein. It prefers the substrate of lacto-N-neotetraose, and is involved in the biosynthesis of poly-N-acetyllactosamine chains.[7]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000170340Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000051650Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Zhou D, Dinter A, Gutierrez Gallego R, Kamerling JP, Vliegenthart JF, Berger EG, Hennet T (Mar 1999). "A β-1,3-N-acetylglucosaminyltransferase with poly-N-acetyllactosamine synthase activity is structurally related to β-1,3-galactosyltransferases". Proc Natl Acad Sci U S A. 96 (2): 406–11. Bibcode:1999PNAS...96..406Z. doi:10.1073/pnas.96.2.406. PMC 15149. PMID 9892646.
  6. ^ Shiraishi N, Natsume A, Togayachi A, Endo T, Akashima T, Yamada Y, Imai N, Nakagawa S, Koizumi S, Sekine S, Narimatsu H, Sasaki K (May 2001). "Identification and characterization of three novel beta 1,3-N-acetylglucosaminyltransferases structurally related to the beta 1,3-galactosyltransferase family". J Biol Chem. 276 (5): 3498–507. doi:10.1074/jbc.M004800200. PMID 11042166.
  7. ^ a b "Entrez Gene: B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2".
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Further reading

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