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Benzathine

From Wikipedia, the free encyclopedia
Benzathine
Names
Preferred IUPAC name
N1,N2-Dibenzylethane-1,2-diamine
Other names
N,N′-bis(phenylmethyl)ethane-1,2-diamine
Identifiers
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
ECHA InfoCard 100.004.918 Edit this at Wikidata
UNII
  • InChI=1S/C16H20N2/c1-3-7-15(8-4-1)13-17-11-12-18-14-16-9-5-2-6-10-16/h1-10,17-18H,11-14H2 checkY
    Key: JUHORIMYRDESRB-UHFFFAOYSA-N checkY
  • InChI=1/C16H20N2/c1-3-7-15(8-4-1)13-17-11-12-18-14-16-9-5-2-6-10-16/h1-10,17-18H,11-14H2
    Key: JUHORIMYRDESRB-UHFFFAOYAS
  • C1=CC=C(C=C1)CNCCNCC2=CC=CC=C2
Properties
C16H20N2
Molar mass 240.343 g/mol
Melting point 26 °C
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Benzathine is a diamine used as a component in some medications including benzathine phenoxymethylpenicillin and benzathine benzylpenicillin. It stabilizes penicillins and increases the half-life.[1]

References

[edit]
  1. ^ Kreuzig, Franz (1982). Penicillin-G Benzathine. Analytical Profiles of Drug Substances. Vol. 11. pp. 463–482. doi:10.1016/S0099-5428(08)60272-5. ISBN 978-0-12-260811-7.