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CD3EAP

From Wikipedia, the free encyclopedia
POLR1G
Identifiers
AliasesPOLR1G, ASE-1, ASE1, CAST, PAF49, CD3e molecule associated protein, RPA34, RNA polymerase I subunit G, CD3EAP
External IDsOMIM: 107325; MGI: 1917583; HomoloGene: 17107; GeneCards: POLR1G; OMA:POLR1G - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_012099
NM_001297590

NM_145822

RefSeq (protein)

NP_001284519
NP_036231

NP_665821

Location (UCSC)Chr 19: 45.41 – 45.41 MbChr 7: 19.09 – 19.09 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

DNA-directed RNA polymerase I subunit RPA34 is an enzyme that in humans is encoded by the CD3EAP gene.[5][6][7][8]

Interactions

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CD3EAP has been shown to interact with T-cell surface glycoprotein CD3 epsilon chain,[5] POLR1E[7] and POLR1C.[7]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000117877Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000047649Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ a b Yamazaki T, Hamano Y, Tashiro H, Itoh K, Nakano H, Miyatake S, Saito T (Jul 1999). "CAST, a novel CD3epsilon-binding protein transducing activation signal for interleukin-2 production in T cells". J Biol Chem. 274 (26): 18173–80. doi:10.1074/jbc.274.26.18173. PMID 10373416.
  6. ^ Whitehead CM, Winkfein RJ, Fritzler MJ, Rattner JB (Mar 1998). "ASE-1: a novel protein of the fibrillar centres of the nucleolus and nucleolus organizer region of mitotic chromosomes". Chromosoma. 106 (8): 493–502. doi:10.1007/s004120050271. PMID 9426281. S2CID 10684078.
  7. ^ a b c Yamamoto K, Yamamoto M, Hanada K, Nogi Y, Matsuyama T, Muramatsu M (Jun 2004). "Multiple protein-protein interactions by RNA polymerase I-associated factor PAF49 and role of PAF49 in rRNA transcription". Mol Cell Biol. 24 (14): 6338–49. doi:10.1128/MCB.24.14.6338-6349.2004. PMC 434256. PMID 15226435.
  8. ^ "Entrez Gene: CD3EAP CD3e molecule, epsilon associated protein".

Further reading

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