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CHST11

From Wikipedia, the free encyclopedia
CHST11
Identifiers
AliasesCHST11, C4ST, C4ST-1, C4ST1, HSA269537, carbohydrate (chondroitin 4) sulfotransferase 11, carbohydrate sulfotransferase 11, OCBMD
External IDsOMIM: 610128; MGI: 1927166; HomoloGene: 56808; GeneCards: CHST11; OMA:CHST11 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_018413
NM_001173982

NM_021439

RefSeq (protein)

NP_001167453
NP_060883
NP_060883.1

NP_067414

Location (UCSC)Chr 12: 104.46 – 104.76 MbChr 10: 82.82 – 83.03 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Carbohydrate sulfotransferase 11 is an enzyme that in humans is encoded by the CHST11 gene.[5][6]

Clinical relevance

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Mutations in this gene have been associated to susceptibility for osteoarthritis.[7]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000171310Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000034612Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Hiraoka N, Nakagawa H, Ong E, Akama TO, Fukuda MN, Fukuda M (Jun 2000). "Molecular cloning and expression of two distinct human chondroitin 4-O-sulfotransferases that belong to the HNK-1 sulfotransferase gene family". The Journal of Biological Chemistry. 275 (26): 20188–96. doi:10.1074/jbc.M002443200. PMID 10781601.
  6. ^ "Entrez Gene: CHST11 carbohydrate (chondroitin 4) sulfotransferase 11".
  7. ^ Zeggini E, Panoutsopoulou K, Southam L, Rayner NW, Day-Williams AG, Lopes MC, et al. (Sep 2012). "Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study". Lancet. 380 (9844): 815–23. doi:10.1016/S0140-6736(12)60681-3. PMC 3443899. PMID 22763110.
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Further reading

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