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CST9L

From Wikipedia, the free encyclopedia
CST9L
Identifiers
AliasesCST9L, CTES7B, bA218C14.1, cystatin 9-like, cystatin 9 like
External IDsOMIM: 616536; MGI: 1340053; HomoloGene: 49222; GeneCards: CST9L; OMA:CST9L - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_080610

NM_009979

RefSeq (protein)

NP_542177

NP_034109

Location (UCSC)Chr 20: 23.56 – 23.57 MbChr 2: 148.68 – 148.68 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Cystatin-9-like is a protein that in humans is encoded by the CST9L gene.[5]

The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes a protein similar to mouse cystatin 9. Based on its testis-specific expression, it is likely to have a role in tissue reorganization during early testis development.[5]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000101435Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000027445Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ a b "Entrez Gene: CST9L cystatin 9-like (mouse)".

Further reading

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