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Carlotta Guiducci

From Wikipedia, the free encyclopedia
Professor
Carlotta Guiducci
Born1977 (age 46–47)
CitizenshipItaly
OccupationPrincipal investigator
AwardsIntel Early Career Faculty Honor Program Award
Academic background
EducationElectrical engineering
Electronic engineering
Alma materUniversity of Bologna
Academic work
DisciplineEngineering
Sub-disciplineBion-engineering
InstitutionsÉcole Polytechnique Fédérale de Lausanne (EPFL)
Main interestsAnalytical microsystems
Lab-on-a-chip devices
Portable DNA-based analytics
Websitehttps://clse.epfl.ch/

Carlotta Guiducci (born 1977) is an Italian bio-engineer. Her research is invested in bio-molecular analysis based on lab-on-a-chip devices. She is an Associate Professor at EPFL (École polytechnique fédérale de Lausanne) and head of the Laboratory of Life Sciences Electronics located at EPFL's Lausanne campus.[1][2]

Career

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Guiducci studied electrical and electronics engineering at University of Bologna and received her Master's degree in 2001. In 2005, she gained a PhD degree in electrical engineering from Department of Electronics, Computer Sciences and Systems (DEIS) at University of Bologna for her work on electronic biosensors and the development of molecular sensors.[3] She joined the Nanobiophysics Laboratory at ParisTech as postdoctoral research fellow in 2005.[4] In 2007, she returned to University of Bologna as research fellow.[5][6]

In 2009, she became a faculty member of the Institute of Bioengineering at the School of Life Sciences at EPFL first as an Assistant Professor, and in 2018, she was promoted as Associate Professor.[1] She is the SwissUp Foundation chair, and the founder and head of Laboratory of Life Sciences Electronics.[7][8][9]

Research

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Guiducci's research centers on biomolecular analysis based on micro-fluidic systems,[10] and on novel personalized medicine approaches.[8][11] She is specialized in the integration and interfacing of analytic lab-on-a-chip devices that incorporate full-fledged laboratory equipment on a miniature scale.[12] She is developing miniaturized portable devices for DNA-based analytics,[11] high-throughput cytometry[13] and single-cell analysis.[14]

Selected works

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  • Stagni, Claudio; Guiducci, Carlotta; Benini, Luca; Ricco, Bruno; Carrara, Sandro; Samori, Bruno; Paulus, Christian; Schienle, Meinrad; Augustyniak, Marcin; Thewes, Roland (2006). "CMOS DNA Sensor Array with Integrated A/D Conversion Based on Label-Free Capacitance Measurement". IEEE Journal of Solid-State Circuits. 41 (12): 2956–2964. Bibcode:2006IJSSC..41.2956S. doi:10.1109/JSSC.2006.884867. S2CID 41863919.
  • Cagnin, Stefano; Caraballo, Marcelo; Guiducci, Carlotta; Martini, Paolo; Ross, Marty; Santaana, Mark; Danley, David; West, Todd; Lanfranchi, Gerolamo (2009). "Overview of Electrochemical DNA Biosensors: New Approaches to Detect the Expression of Life". Sensors. 9 (4): 3122–3148. Bibcode:2009Senso...9.3122C. doi:10.3390/s90403122. PMC 3348825. PMID 22574066.
  • Benini, L.; Farella, E.; Guiducci, C. (2006). "Wireless sensor networks: Enabling technology for ambient intelligence". Microelectronics Journal. 37 (12): 1639–1649. doi:10.1016/j.mejo.2006.04.021.
  • Guiducci, C. (2004). "DNA detection by integrable electronics". Biosensors and Bioelectronics. 19 (8): 781–787. doi:10.1016/S0956-5663(03)00266-5. PMID 15128096.
  • Stagni, Claudio; Guiducci, Carlotta; Benini, Luca; Ricco, Bruno; Carrara, Sandro; Paulus, Christian; Schienle, Meinrad; Thewes, Roland (2007). "A Fully Electronic Label-Free DNA Sensor Chip". IEEE Sensors Journal. 7 (4): 577–585. Bibcode:2007ISenJ...7..577S. doi:10.1109/JSEN.2007.891990. S2CID 32564939.
  • Cappi, Giulia; Spiga, Fabio M.; Moncada, Yessica; Ferretti, Anna; Beyeler, Michael; Bianchessi, Marco; Decosterd, Laurent; Buclin, Thierry; Guiducci, Carlotta (2015). "Label-Free Detection of Tobramycin in Serum by Transmission-Localized Surface Plasmon Resonance" (PDF). Analytical Chemistry. 87 (10): 5278–5285. doi:10.1021/acs.analchem.5b00389. PMID 25811093.
  • Lime, F.; Guiducci, C.; Clerc, R.; Ghibaudo, G.; Leroux, C.; Ernst, T. (2003). "Characterization of effective mobility by split C(V) technique in N-MOSFETs with ultra-thin gate oxides". Solid-State Electronics. 47 (7): 1147–1153. Bibcode:2003SSEle..47.1147L. doi:10.1016/S0038-1101(03)00049-2.

References

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  1. ^ a b "11 professors appointed at ETH Zurich and EPFL | ETH-Board". www.ethrat.ch. Retrieved 2020-10-01.
  2. ^ "Prof. Carlotta Guiducci". www.epfl.ch. Retrieved 2020-10-01.
  3. ^ Guiducci, C (2004-03-15). "DNA detection by integrable electronics". Biosensors and Bioelectronics. 19 (8): 781–787. doi:10.1016/S0956-5663(03)00266-5. PMID 15128096.
  4. ^ "NANOBIOPHYSICS LAB/ People". www.nbp.espci.fr. Retrieved 2020-10-02.
  5. ^ "CARLOTTA GUIDUCCI". 100 Women and Thousands More. Retrieved 2020-10-02.
  6. ^ Guiducci, Carlotta; Nardini, Christine (2008-04-01). "High parallelism, portability, and broad accessibility: Technologies for genomics". ACM Journal on Emerging Technologies in Computing Systems. 4 (1): 1–39. doi:10.1145/1330521.1330524. ISSN 1550-4832. S2CID 6216740.
  7. ^ "CLSE". www.epfl.ch. Retrieved 2020-10-02.
  8. ^ a b "Research at Swiss Up Chair on Engineering". www.epfl.ch. Retrieved 2020-10-02.
  9. ^ "Rencontre avec Carlotta Guiducci - Radio". Play RTS (in French). 22 March 2013. Retrieved 2020-10-02.
  10. ^ Thiriet, Pierre-Emmanuel; Pezoldt, Joern; Gambardella, Gabriele; Keim, Kevin; Deplancke, Bart; Guiducci, Carlotta (2020-03-20). "Selective Retrieval of Individual Cells from Microfluidic Arrays Combining Dielectrophoretic Force and Directed Hydrodynamic Flow". Micromachines. 11 (3): 322. doi:10.3390/mi11030322. ISSN 2072-666X. PMC 7143322. PMID 32244902.
  11. ^ a b Tenaglia, Enrico; Ferretti, Anna; Decosterd, Laurent A.; Werner, Dominique; Mercier, Thomas; Widmer, Nicolas; Buclin, Thierry; Guiducci, Carlotta (2018-06-30). "Comparison against current standards of a DNA aptamer for the label-free quantification of tobramycin in human sera employed for therapeutic drug monitoring". Journal of Pharmaceutical and Biomedical Analysis. 159: 341–347. doi:10.1016/j.jpba.2018.06.061. PMID 30025299. S2CID 51700744.
  12. ^ Guiducci, Carlotta (2017-07-27). "Integrated electrical sensing for high-throughput bioanalytics". 2017 IEEE International Conference on IC Design and Technology (ICICDT). Austin, TX, USA: IEEE. pp. 1–3. doi:10.1109/ICICDT.2017.7993520. ISBN 978-1-5090-4502-0. S2CID 44830895.
  13. ^ Rollo, Enrica; Tenaglia, Enrico; Genolet, Raphaël; Bianchi, Elena; Harari, Alexandre; Coukos, George; Guiducci, Carlotta (2017-08-15). "Label-free identification of activated T lymphocytes through tridimensional microsensors on chip". Biosensors and Bioelectronics. 94: 193–199. doi:10.1016/j.bios.2017.02.047. PMID 28284079.
  14. ^ Keim, Kevin; Rashed, Mohamed Z.; Kilchenmann, Samuel C.; Delattre, Aurélien; Gonçalves, António F.; Éry, Paul; Guiducci, Carlotta (2019-06-03). "On-chip technology for single-cell arraying, electrorotation-based analysis and selective release". Electrophoresis. 40 (14): 1830–1838. doi:10.1002/elps.201900097. ISSN 0173-0835. PMC 6771916. PMID 31111973.
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