Crislyn D'Souza-Schorey

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Crislyn D'Souza-Schorey
Born
Bombay, India
Academic background
EducationUniversity of Texas Health Science Center at San Antonio (PhD, 1992)
Academic work
InstitutionsUniversity of Notre Dame

Crislyn D'Souza-Schorey is an American-Indian biologist. She is the Morris Pollard Professor and former Department Chair of Biological Sciences at the University of Notre Dame. D'Souza-Schorey researches how membrane trafficking impacts cell motility under normal conditions and in disease states.

Early life and education[edit]

D'Souza-Schorey was born and raised in Bombay, India. She completed her bachelor's degree in India at the age of 19 and remained there for her Master's degree.[1] D'Souza-Schorey then moved to the United States where she completed her PhD at the University of Texas Health Science Center at San Antonio in 1992.[2]

Following her PhD, D'Souza-Schorey accepted a postdoctoral fellowship at Washington University School of Medicine. In this role, she began researching therapeutics and diagnostics tools to cure cancer, specifically ARF6.[1] Her research led to the discovery that ARF6 played a role in endosomal membrane trafficking and also governed structural organization at the cell surface.[3]

Career[edit]

Following her postdoctoral fellowship, D'Souza-Schorey joined the University of Notre Dame faculty as the Walther Cancer Institute Junior Chair in 1998.[4] Upon starting her own laboratory, she found that ARF6 regulated cell-cell contact.[3] D'Souza-Schorey then began looking into how epithelial cells developed by examining how the protein affected and altered tumor cells.[5][6]

In 2009, she published a paper which identified a unique population of microvesicles that are enriched in proteases-mediators of tissue degradation. The release of these microvesicles provides a mechanism of tissue breakdown and remodeling at distant sites.[7] As a result of her academic accomplishments, D'Souza-Schorey was elected a Fellow of the American Association for the Advancement of Science in 2012.[8]

In 2014, D'Souza-Schorey became the first woman to be appointed the Department Chair of Biological Sciences at Notre Dame.[9][10] While serving in this role, she received a patent for a method for detecting invasive microvesicles derived from tumor cells.[11] In 2020, D'Souza-Schorey was recognized with the school's Faculty Award for her "outstanding service to the University such as through leadership activities, mentoring faculty colleagues, or exemplary dedication to students."[12] Later that year, she stepped down as department chair and was replaced by Jason Rohr.[13] In 2022, D'Souza-Schorey was named co-editor-in-chief of the Federation of American Societies for Experimental Biology BioAdvances journal.[14]

Personal life[edit]

D'Souza-Schorey is married to biologist Jeffrey Schorey and they have one son together.[9]

References[edit]

  1. ^ a b McCool, Deanna (March 2018). "Women Who Lead: Crislyn D'Souza-Schorey". University of Notre Dame. Retrieved May 5, 2023.
  2. ^ "Crislyn D'Souza-Schorey". University of Notre Dame. Retrieved May 5, 2023.
  3. ^ a b Nybo, Kristie (2009). "Passion Breeds Opportunities: Crislyn D'Souza-Schorey". BioTechniques. 46 (3). Future Science: 155. doi:10.2144/000113129. Retrieved May 5, 2023.
  4. ^ "LECTURERS AT THE JEFFERSON EDUCATIONAL SOCIETY". Jefferson Educational Society. Retrieved May 5, 2023.
  5. ^ Ochstein, Jennifer (May 6, 2007). "Researcher looks at epithelial cells". The South Bend Tribune. Retrieved May 5, 2023 – via newspapers.com.
  6. ^ Ochstein, Jennifer (May 6, 2007). "Cells". The South Bend Tribune. Retrieved May 5, 2023 – via newspapers.com.
  7. ^ Gilroy, William G. (November 4, 2009). "New Notre Dame study provides insights into the molecular basis of tumor cell behavior". University of Notre Dame. Retrieved May 5, 2023.
  8. ^ "AAAS Members Elected as Fellows". American Association for the Advancement of Science. November 30, 2012. Retrieved May 5, 2023.
  9. ^ a b Frazier, Matt (October 30, 2019). "Up Close with the Department Chair". University of Notre Dame. Retrieved May 5, 2023.
  10. ^ Stowe, Gene (March 30, 2014). "D'Souza-Schorey named chair of the Department of Biological Sciences". University of Notre Dame. Retrieved May 5, 2023.
  11. ^ Stowe, Gene (Spring 2017). "Discoveries lead to new patents" (PDF). University of Notre Dame. p. 11. Retrieved May 5, 2023.
  12. ^ "Crislyn D'Souza-Schorey Receives 2020 Faculty Award". University of Notre Dame. May 29, 2020. Retrieved May 5, 2023.
  13. ^ Csomo McCool, Deanna (June 15, 2020). "Rohr to succeed D'Souza-Schorey as chair in Department of Biological Sciences". University of Notre Dame. Retrieved May 5, 2023.
  14. ^ Csomo Ferrell, Deanna (January 18, 2022). "D'Souza-Schorey and Smith named as journal editors". University of Notre Dame. Retrieved May 5, 2023.

External links[edit]

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