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Diaminopropionate ammonia-lyase

From Wikipedia, the free encyclopedia
diaminopropionate ammonia-lyase
Identifiers
EC no.4.3.1.15
CAS no.51901-19-0
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
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PMCarticles
PubMedarticles
NCBIproteins

The enzyme diaminopropionate ammonia-lyase (EC 4.3.1.15) catalyzes the chemical reaction

2,3-diaminopropanoate + H2O pyruvate + 2 NH3

This enzyme belongs to the family of lyases, specifically ammonia lyases, which cleave carbon-nitrogen bonds. The systematic name of this enzyme class is 2,3-diaminopropanoate ammonia-lyase (adding water; pyruvate-forming). Other names in common use include diaminopropionatase, α,β-diaminopropionate ammonia-lyase, 2,3-diaminopropionate ammonia-lyase, and 2,3-diaminopropanoate ammonia-lyase. It employs one cofactor, pyridoxal phosphate.

References

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  • Nagasawa T, Tanizawa K, Satoda T, Yamada H (1988). "Diaminopropionate ammonia-lyase from Salmonella typhimurium. Purification and characterization of the crystalline enzyme, and sequence determination of the pyridoxal 5'-phosphate binding peptide". J. Biol. Chem. 263 (2): 958–64. PMID 3275662.