Draft:Puberulic Acid

Puberulic Acid
One tautomer of puberulic acid	Another tautomer of puberulic acid
Names
	IUPAC name 4,5,6-trihydroxy-3-oxocyclohepta-1,4,6-triene-1-carboxylic acid
Identifiers
CAS Number	99-23-0 ;
3D model (JSmol)	Interactive image;
ChEMBL	ChEMBL3588897 ;
	SMILES C1=C(C=C(C(=C(C1=O)O)O)O)C(=O)O;
Properties
Chemical formula	C8H6O6
Molar mass	198.13 g/mol
Density	2.0 to 2.2 g/ml
Boiling point	166.4 to 246.4 °C (331.5 to 475.5 °F; 439.5 to 519.5 K) (760 mmHg)
Hazards
	GHS labelling:
Pictograms
Signal word	Danger
Hazard statements	H314, H317, H410
Precautionary statements	P260, P261, P264, P272, P273, P280, P301+P330+P331, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P310, P333+P313, P363, P391, P405, P501
Flash point	112 °C (234 °F; 385 K)
Related compounds
Related compounds	Hinokitiol (4-isopropyl-tropolone)
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). verify (what is ?) Infobox references

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Last edited by Pygos (talk | contribs) 2 seconds ago. (Update)

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Puberulic acid is an organic compound. derived from tropolone. It is toxic and was responsible for cases of poisoning incidents., and is secreted by blue mold.^[2] It has been investigated for its antimalarial properties.^[3]

Synthesis and reactions

Biological effects

References

^ "Tropolone". pubchem.ncbi.nlm.nih.gov.
^ Davis RA, Ueno H (2024-06-28). "Deaths Linked to Japanese Supplement Suddenly Rise to 80". The New York Times. ISSN 0362-4331. Retrieved 2024-07-21.
^ Iwatsuki M, Takada S, Mori M, Ishiyama A, Namatame M, Nishihara-Tsukashima A, Nonaka K, Masuma R, Otoguro K, Shiomi K, Ōmura S (February 2011). "In vitro and in vivo antimalarial activity of puberulic acid and its new analogs, viticolins A–C, produced by Penicillium sp. FKI-4410". The Journal of Antibiotics. 64 (2): 183–188. doi:10.1038/ja.2010.124. ISSN 1881-1469.

[1] "Tropolone". pubchem.ncbi.nlm.nih.gov.

[2] Davis RA, Ueno H (2024-06-28). "Deaths Linked to Japanese Supplement Suddenly Rise to 80". The New York Times. ISSN 0362-4331. Retrieved 2024-07-21.

[3] Iwatsuki M, Takada S, Mori M, Ishiyama A, Namatame M, Nishihara-Tsukashima A, Nonaka K, Masuma R, Otoguro K, Shiomi K, Ōmura S (February 2011). "In vitro and in vivo antimalarial activity of puberulic acid and its new analogs, viticolins A–C, produced by Penicillium sp. FKI-4410". The Journal of Antibiotics. 64 (2): 183–188. doi:10.1038/ja.2010.124. ISSN 1881-1469.

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