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FAAH2

From Wikipedia, the free encyclopedia
FAAH2
Identifiers
AliasesFAAH2, AMDD, fatty acid amide hydrolase 2
External IDsOMIM: 300654; HomoloGene: 45263; GeneCards: FAAH2; OMA:FAAH2 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_174912
NM_001353840
NM_001353841

n/a

RefSeq (protein)

NP_777572
NP_001340769
NP_001340770

n/a

Location (UCSC)Chr X: 57.29 – 57.49 Mbn/a
PubMed search[2]n/a
Wikidata
View/Edit Human

Fatty acid amide hydrolase 2 or FAAH2 is a member of the serine hydrolase family of enzymes.[3]

Fatty acid amide hydrolase 2 degrades endocannabinoids and defects in this enzyme have been associated with neurologic and psychiatric disorders.[4]

See also

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References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000165591Ensembl, May 2017
  2. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. ^ Wei BQ, Mikkelsen TS, McKinney MK, Lander ES, Cravatt BF (December 2006). "A second fatty acid amide hydrolase with variable distribution among placental mammals". The Journal of Biological Chemistry. 281 (48): 36569–78. doi:10.1074/jbc.M606646200. PMID 17015445.
  4. ^ Sirrs S, van Karnebeek CD, Peng X, Shyr C, Tarailo-Graovac M, Mandal R, et al. (March 2015). "Defects in fatty acid amide hydrolase 2 in a male with neurologic and psychiatric symptoms". Orphanet Journal of Rare Diseases. 10: 38. doi:10.1186/s13023-015-0248-3. PMC 4423390. PMID 25885783.
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