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Protein-coding gene in the species Homo sapiens
FLT3 interacting zinc finger 1 is a protein that in humans is encoded by the FIZ1 gene .
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Function [ edit ]
This gene encodes zinc finger protein, which interacts with a receptor tyrosine kinase involved in the regulation of hematopoietic and lymphoid cells. This gene product also interacts with a transcription factor that regulates the expression of rod-specific genes in retina. [provided by RefSeq, Jul 2008].
References [ edit ]
Further reading [ edit ]
Mitton KP, Swain PK, Khanna H, Dowd M, Apel IJ, Swaroop A (February 2003). "Interaction of retinal bZIP transcription factor NRL with Flt3-interacting zinc-finger protein Fiz1: possible role of Fiz1 as a transcriptional repressor" . Hum. Mol. Genet . 12 (4): 365–73. doi :10.1093/hmg/ddg035 . PMID 12566383 .
Mali RS, Zhang X, Hoerauf W, Doyle D, Devitt J, Loffreda-Wren J, Mitton KP (February 2007). "FIZ1 is expressed during photoreceptor maturation, and synergizes with NRL and CRX at rod-specific promoters in vitro" . Exp. Eye Res . 84 (2): 349–60. doi :10.1016/j.exer.2006.10.009 . PMC 5066392 . PMID 17141759 .
This article incorporates text from the United States National Library of Medicine , which is in the public domain .