Jump to content

FLVCR2

From Wikipedia, the free encyclopedia
FLVCR2
Identifiers
AliasesFLVCR2, C14orf58, CCT, EPV, FLVCRL14q, MFSD7C, PVHH, feline leukemia virus subgroup C cellular receptor family member 2, SLC49A2, FLVCR heme transporter 2
External IDsOMIM: 610865; MGI: 2384974; HomoloGene: 9840; GeneCards: FLVCR2; OMA:FLVCR2 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_017791
NM_001195283

NM_145447

RefSeq (protein)

NP_001182212
NP_060261

NP_663422

Location (UCSC)Chr 14: 75.58 – 75.66 MbChr 12: 85.79 – 85.86 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Feline leukemia virus subgroup C cellular receptor family, member 2 is a protein that in humans is encoded by the FLVCR2 gene.[5]

Function

[edit]

This gene encodes a member of the major facilitator superfamily. The encoded transmembrane protein is a calcium transporter. Unlike the related protein feline leukemia virus subgroup C receptor 1 (FLVCR1), the protein encoded by this locus does not bind to feline leukemia virus subgroup C envelope protein. The encoded protein may play a role in development of brain vascular endothelial cells, as mutations at this locus have been associated with proliferative vasculopathy and hydranencephaly-hydrocephaly syndrome.

References

[edit]
  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000119686Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000034258Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: Feline leukemia virus subgroup C cellular receptor family, member 2". NCBI.

Further reading

[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.