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Formate kinase

From Wikipedia, the free encyclopedia
formate kinase
Identifiers
EC no.2.7.2.6
CAS no.9026-65-7
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
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PMCarticles
PubMedarticles
NCBIproteins

In enzymology, a formate kinase (EC 2.7.2.6) is an enzyme that catalyzes the chemical reaction

ATP + formate ADP + formyl phosphate

Thus, the two substrates of this enzyme are ATP and formate, whereas its two products are ADP and formyl phosphate.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with a carboxy group as acceptor. The systematic name of this enzyme class is ATP:formate phosphotransferase. This enzyme participates in glyoxylate and dicarboxylate metabolism.

References

[edit]
  • Sly WS, Stadtman ER (1963). "Formate metabolism. II. Enzymatic synthesis of formyl phosphate and formyl coenzyme A in Clostridium cylindrosporum". J. Biol. Chem. 238: 2639–2647.