Jump to content

Formimidoyltransferase cyclodeaminase

From Wikipedia, the free encyclopedia
formimidoyltransferase cyclodeaminase
Formiminotransferase cyclodeaminase homooctamer, Rattus norvegicus
Identifiers
SymbolFTCD
Alt. namesformiminotransferase cyclodeaminase
NCBI gene10841
HGNC3974
OMIM606806
RefSeqNM_006657
UniProtO95954
Other data
LocusChr. 21 q22.3
Search for
StructuresSwiss-model
DomainsInterPro

Formimidoyltransferase cyclodeaminase or formiminotransferase cyclodeaminase (gene symbol FTCD in humans) is a bifunctional enzyme that catalyzes the following reactions:[1]

Its name comes from the two activities it catalyzes.

Role in pathology

[edit]

Mutations of the FTCD gene cause glutamate formiminotransferase deficiency.[1]

See also

[edit]

References

[edit]
  1. ^ a b "Glutamate formiminotransferase deficiency". NIH. GARD. August 10, 2016. Retrieved December 21, 2020.