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Fumigaclavine A dimethylallyltransferase

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Fumigaclavine A dimethylallyltransferase
Identifiers
EC no.2.5.1.100
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
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NCBIproteins

Fumigaclavine A dimethylallyltransferase (EC 2.5.1.100, FgaPT1) is an enzyme with systematic name dimethylallyl-diphosphate:fumigaclavine A dimethylallyltransferase.[1] This enzyme catalyses the following chemical reaction

fumigaclavine A + dimethylallyl diphosphate fumigaclavine C + diphosphate

Fumigaclavine C is an ergot alkaloid produced by some fungi of the Trichocomaceae family.

References

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  1. ^ Unsöld IA, Li SM (January 2006). "Reverse prenyltransferase in the biosynthesis of fumigaclavine C in Aspergillus fumigatus: gene expression, purification, and characterization of fumigaclavine C synthase FGAPT1". ChemBioChem. 7 (1): 158–64. doi:10.1002/cbic.200500318. PMID 16397874.
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