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GANAB

From Wikipedia, the free encyclopedia
GANAB
Identifiers
AliasesGANAB, G2AN, GLUII, GIIA, glucosidase II alpha subunit, PKD3
External IDsOMIM: 104160; MGI: 1097667; HomoloGene: 5426; GeneCards: GANAB; OMA:GANAB - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001293621
NM_008060

RefSeq (protein)

NP_001280550
NP_032086

Location (UCSC)Chr 11: 62.62 – 62.65 MbChr 19: 8.88 – 8.89 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Neutral alpha-glucosidase AB is an enzyme that in humans is encoded by the GANAB gene.[5][6][7]

Interactions

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GANAB has been shown to interact with PTPRC.[8][9][10]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000089597Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000071650Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Treml K, Meimaroglou D, Hentges A, Bause E (May 2000). "The alpha- and beta-subunits are required for expression of catalytic activity in the hetero-dimeric glucosidase II complex from human liver". Glycobiology. 10 (5): 493–502. doi:10.1093/glycob/10.5.493. PMID 10764838.
  6. ^ Martiniuk F, Smith M, Ellenbogen A, Desnick RJ, Astrin K, Mitra J, Hirschhorn R (July 1983). "Assignment of the gene for neutral alpha-glucosidase AB to chromosome 11". Cytogenet Cell Genet. 35 (2): 110–6. doi:10.1159/000131851. PMID 6342981. S2CID 46749795.
  7. ^ "Entrez Gene: GANAB glucosidase, alpha; neutral AB".
  8. ^ Arendt CW, Ostergaard HL (May 1997). "Identification of the CD45-associated 116-kDa and 80-kDa proteins as the alpha- and beta-subunits of alpha-glucosidase II". J. Biol. Chem. 272 (20): 13117–25. doi:10.1074/jbc.272.20.13117. PMID 9148925.
  9. ^ Baldwin TA, Gogela-Spehar M, Ostergaard HL (October 2000). "Specific isoforms of the resident endoplasmic reticulum protein glucosidase II associate with the CD45 protein-tyrosine phosphatase via a lectin-like interaction". J. Biol. Chem. 275 (41): 32071–6. doi:10.1074/jbc.M003088200. PMID 10921916.
  10. ^ Baldwin TA, Ostergaard HL (October 2001). "Developmentally regulated changes in glucosidase II association with, and carbohydrate content of, the protein tyrosine phosphatase CD45". J. Immunol. 167 (7): 3829–35. doi:10.4049/jimmunol.167.7.3829. PMID 11564800.

Further reading

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