Jump to content

GAS2L1

From Wikipedia, the free encyclopedia
GAS2L1
Identifiers
AliasesGAS2L1, GAR22, growth arrest specific 2 like 1
External IDsOMIM: 602128; MGI: 1926176; HomoloGene: 4733; GeneCards: GAS2L1; OMA:GAS2L1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001190406
NM_001190408
NM_030228
NM_144560

RefSeq (protein)

NP_001265659
NP_006469
NP_689422
NP_689423
NP_001349914

NP_001177335
NP_001177337
NP_084504
NP_653146

Location (UCSC)Chr 22: 29.31 – 29.31 MbChr 11: 5 – 5.02 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

GAS2-like protein 1 is a protein that in humans is encoded by the GAS2L1 gene.[5][6][7][8]

The protein encoded by this gene, a member of the GAS2 family, is similar in sequence to the mouse protein Gas2, an actin-associated protein expressed at high levels in growth-arrested cells. Expression of the mouse Gas2 gene is negatively regulated by serum and growth factors. Three transcript variants encoding two different isoforms have been found for this gene.[8]

References

[edit]
  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000185340Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000034201Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Zucman-Rossi J, Legoix P, Thomas G (Mar 1997). "Identification of new members of the Gas2 and Ras families in the 22q12 chromosome region". Genomics. 38 (3): 247–54. doi:10.1006/geno.1996.0625. PMID 8975699.
  6. ^ Goriounov D, Leung CL, Liem RK (Feb 2003). "Protein products of human Gas2-related genes on chromosomes 17 and 22 (hGAR17 and hGAR22) associate with both microfilaments and microtubules". J Cell Sci. 116 (Pt 6): 1045–58. doi:10.1242/jcs.00272. PMID 12584248.
  7. ^ Brancolini C, Bottega S, Schneider C (Jul 1992). "Gas2, a growth arrest-specific protein, is a component of the microfilament network system". J Cell Biol. 117 (6): 1251–61. doi:10.1083/jcb.117.6.1251. PMC 2289493. PMID 1607387.
  8. ^ a b "Entrez Gene: GAS2L1 growth arrest-specific 2 like 1".

Further reading

[edit]