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GJD3

From Wikipedia, the free encyclopedia
GJD3
Identifiers
AliasesGJD3, CX31.9, Cx30.2, GJA11, GJC1, gap junction protein delta 3
External IDsOMIM: 607425; MGI: 2384150; HomoloGene: 17530; GeneCards: GJD3; OMA:GJD3 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_152219

NM_178596

RefSeq (protein)

NP_689343

NP_848711

Location (UCSC)Chr 17: 40.36 – 40.36 MbChr 11: 98.87 – 98.87 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Gap junction delta-2 (GJD2), also known as connexin-36 (Cx36) or gap junction alpha-9 (GJA9), is a protein that in humans is encoded by the GJD2 gene.[5]

Function

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This gene is a member of the large family of connexins that are required for the formation of gap junctions. Six connexin monomers form a hemichannel, or connexon, on the cell surface. This connexon can interact with a connexon from a neighboring cell, thus forming a channel linking the cytoplasm of the 2 cells.[5]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000183153Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000047197Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ a b "Entrez Gene: gap junction protein".

Further reading

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.