Graham Cooke

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For the Australian rugby union player, see Graham Cooke (rugby union).
Graham Cooke
FRCP, FMedSci
Born
Hemel Hempstead, Hertfordshire, England
NationalityBritish
EducationWatford Boys Grammar School
Alma materSt John's College, Cambridge
Worcester College, Oxford
University of KwaZulu-Natal
Scientific career
FieldsInfectious diseases
InstitutionsImperial College London
Thesis Host genetic of susceptibility to tuberculosis (2003)

Professor Graham Cooke FRCP FMedSci is a clinician scientist and NIHR Professor of Infectious Diseases at the Wright-Fleming Institute of Imperial College London.[1] He is best known for his work on viral hepatitis, particularly hepatitis C.[2][3]

Early life and education[edit]

Educated at Watford Grammar School for Boys, he studied natural sciences and medicine at University of Cambridge. Later he undertook his doctoral studies with Adrian V. S. Hill at the Wellcome Center for Human Genetics, studying human genetic variation and its role in susceptibility to tuberculosis.[4]

Research and career[edit]

After specialist training in London, Cooke was based at the Africa Centre for Health and Population Studies, Mtubatuba (now AHRI) before moving to Imperial College.[5] His work has focussed on HIV, tuberculosis and viral hepatitis.[1] In 2016 he led publication of global estimates of viral hepatitis disease burden and has had a prominent role in efforts to raise the profile of viral hepatitis globally, leading the commission on viral hepatitis elimination in 2019.[1] He has run randomised trials in the UK and Vietnam contributing insights into host-virus interactions and treatment outcomes.[6]

COVID-19[edit]

During the COVID-19 pandemic, Cooke was an investigator on the REACT (Real-time Assessment of Community Transmission) programme, the largest study of consented individuals during the pandemic.[7][8] The programme made important contributions to government policy and informed decisions on relaxation of national restrictions and vaccine delivery.[9]

With Chris Toumazou, he led the development of the COVIDnudge diagnostic,[10] implemented in the NHS in 2020.[11]

Other roles[edit]

He has advocated for access to affordable medicines.[12] He became a member of the WHO committee for Selection and Use of Essential Medicines in 2015 and chairman in 2019.[1][13] In 2021, he was appointed non-executive director and Deputy Chair of the Medicines and Healthcare products Regulatory Agency Board (MHRA).[14]

Honours[edit]

He is a Fellow of the Royal College of Physicians (2012),[15] National Institute for Health and Care Research (NIHR) Research Professor (2017), Fellow of the Academy of Medical Sciences (2023).[16]

References[edit]

  1. ^ a b c d "Home - Professor Graham Cooke". Imperial.ac.uk. Retrieved 5 March 2019.
  2. ^ "Hepatitis C research pioneer wins prestigious award". Imperial.ac.uk. Retrieved 5 March 2019.
  3. ^ "Hepatitis C elimination in people living with HIV in the UK is feasible by 2021, British HIV Association says". Infohep.org. Retrieved 5 March 2019.
  4. ^ "Human genetics and susceptibility to tuberculosis". Retrieved 20 March 2019.
  5. ^ "Graham Cooke". Coalition for Global Hepatitis Elimination. Retrieved 2023-08-14.
  6. ^ Cooke, Graham. "VIETNarms: a multi-arm trial of HCV treatment strategies in Vietnam". ISRCTN. doi:10.1186/isrctn61522291. Retrieved 2023-08-14.
  7. ^ "Find out about REACT". Imperial College London. Retrieved 2023-08-14.
  8. ^ "Largest COVID-19 testing study shows cases are rising across England". Imperial News. 2020-09-11. Retrieved 2023-08-14.
  9. ^ "Real-time surveillance to improve situational awareness of COVID-19: the REACT study". results2021.ref.ac.uk. Retrieved 29 May 2023.
  10. ^ Gibani, MM; Toumazou, C; Sohbati, M; Sahoo, R; Karvela, M; Hon, TK; De Mateo, S; Burdett, A; Leung, KYF; Barnett, J; Orbeladze, A; Luan, S; Pournias, S; Sun, J; Flower, B; Bedzo-Nutakor, J; Amran, M; Quinlan, R; Skolimowska, K; Herrera, C; Rowan, A; Badhan, A; Klaber, R; Davies, G; Muir, D; Randell, P; Crook, D; Taylor, GP; Barclay, W; Mughal, N; Moore, LSP; Jeffery, K; Cooke, GS (November 2020). "Assessing a novel, lab-free, point-of-care test for SARS-CoV-2 (CovidNudge): a diagnostic accuracy study". The Lancet. Microbe. 1 (7): e300–e307. doi:10.1016/S2666-5247(20)30121-X. hdl:10044/1/82918. PMC 7498257. PMID 32964211.
  11. ^ Boseley, Sarah (2020-09-17). "New UK Covid test is effective but won't impact numbers as hoped". The Guardian. ISSN 0261-3077. Retrieved 2023-08-14.
  12. ^ "Initiative to increase access to expensive hepatitis drugs in poorer countries". NIHR Imperial Biomedical Research Centre. 31 July 2019. Retrieved 2023-08-14.
  13. ^ "BBC World Service - World Update, New 'Trojan horse' antibiotic seems promising". BBC. Retrieved 5 March 2019.
  14. ^ "Four Non-Executive Directors appointed to the Medicines and Healthcare products Regulatory Agency Board". gov.uk. Retrieved 30 October 2021.
  15. ^ "Dr Graham Cooke". Imperial College Healthcare NHS Trust. Retrieved 2023-08-14.
  16. ^ "Outstanding biomedical and health researchers elected to Academy of Medical Sciences Fellowship". Academy of Medical Sciences. Retrieved 14 July 2023.
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