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HAGH

From Wikipedia, the free encyclopedia
HAGH
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesHAGH, GLO2, GLX2, GLXII, HAGH1, hydroxyacylglutathione hydrolase
External IDsOMIM: 138760; MGI: 95745; HomoloGene: 3890; GeneCards: HAGH; OMA:HAGH - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001040427
NM_001286249
NM_005326
NM_001363912
NM_001363914

NM_001159626
NM_024284

RefSeq (protein)

NP_001035517
NP_001273178
NP_005317
NP_001350841
NP_001350843

NP_001153098
NP_077246

Location (UCSC)Chr 16: 1.8 – 1.83 MbChr 17: 25.06 – 25.08 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Hydroxyacylglutathione hydrolase, mitochondrial is an enzyme that in humans is encoded by the HAGH gene.[5][6][7]

The enzyme encoded by this gene is classified as a thiolesterase and is responsible for the hydrolysis of S-lactoyl-glutathione to reduced glutathione and D-lactate.[7]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000063854Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000024158Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Mulley JC, Callen DF (Feb 1987). "New regional localisations for HAGH and PGP on human chromosome 16". Hum Genet. 74 (4): 423–4. doi:10.1007/BF00280498. PMID 3025077. S2CID 19620852.
  6. ^ Honey NK, Shows TB (Apr 1982). "Assignment of the glyoxalase II gene (HAGH) to human chromosome 16". Hum Genet. 58 (4): 358–61. doi:10.1007/bf00282815. PMID 7327557. S2CID 10452468.
  7. ^ a b "Entrez Gene: HAGH hydroxyacylglutathione hydrolase".

Further reading

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