HPO

HPO may refer to:

• HPO formalism, an approach to temporal quantum logic
• Hamilton Philharmonic Orchestra, a symphony orchestra based in Ontario, Canada
• High performance organization, a conceptual framework for organizations
• Highway Post Office, of the United States Postal Service
• Homeowner Protection Office, in British Columbia, Canada
• Hpon language, spoken in Burma
• Human Phenotype Ontology
• Humanist Party of Ontario, a political party in Canada
• Hydrogen peroxide, an oxidizer
• Premnaspirodiene oxygenase, an enzyme
• Hippo, a protein kinase involved in the Hippo signaling pathway
• Hyperparameter optimization, a technique used in automated machine learning