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Histidine N-acetyltransferase

From Wikipedia, the free encyclopedia
histidine N-acetyltransferase
Identifiers
EC no.2.3.1.33
CAS no.9027-59-2
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
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PMCarticles
PubMedarticles
NCBIproteins

In enzymology, a histidine N-acetyltransferase (EC 2.3.1.33) is an enzyme that catalyzes the chemical reaction

acetyl-CoA + L-histidine CoA + N-acetyl-L-histidine

Thus, the two substrates of this enzyme are acetyl-CoA and L-histidine, whereas its two products are CoA and N-acetyl-L-histidine.

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is acetyl-CoA:L-histidine N-acetyltransferase. Other names in common use include acetylhistidine synthetase, and histidine acetyltransferase.

References

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  • Baslow MH (December 1966). "N -acetyl-L-histidine synthetase activity from the brain of the killifish". Brain Research. 3 (2): 210–3. doi:10.1016/0006-8993(66)90082-5. PMID 5971525.