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IGF2-AS

From Wikipedia, the free encyclopedia

IGF2-AS
Identifiers
AliasesIGF2-AS, IGF2-AS1, PEG8, IGF2 antisense RNA
External IDsOMIM: 610146; GeneCards: IGF2-AS; OMA:IGF2-AS - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_016412

n/a

RefSeq (protein)

n/a

n/a

Location (UCSC)Chr 11: 2.14 – 2.15 Mbn/a
PubMed search[2]n/a
Wikidata
View/Edit Human

IGF2 antisense RNA is a protein that in humans is encoded by the IGF2-AS gene. [3]

Function

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This gene is expressed in antisense to the insulin-like growth factor 2 (IGF2) gene and is imprinted and paternally expressed. It is thought to be non-coding because the putative protein is not conserved and translation is predicted to trigger nonsense mediated decay (NMD). Transcripts from this gene are produced in tumors and may function to suppress cell growth. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2015].

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000099869Ensembl, May 2017
  2. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. ^ "Entrez Gene: IGF2 antisense RNA". Retrieved 2018-03-07.

Further reading

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.