Karen Christman
Karen Christman | |
|---|---|
 Christman in 2019 | |
| Born | Karen Leigh Christman |
| Alma mater | Northwestern University University of California, San Francisco |
| Scientific career | |
| Institutions | University of California, San Diego University of California, Los Angeles |
| Thesis | In situ engineered myocardial tissue (2003) |
| Academic advisors | Heather Maynard |
| Website | christman |
Karen Leigh Christman is an American bioengineer who is the Associate Dean for Faculty Affairs and the Pierre Galletti Endowed Chair for Bioengineering Innovation at University of California, San Diego.[1][2] Her research considers regenerative medicine and tissue engineering. She was elected a Fellow of the National Academy of Inventors in 2023.
Early life and education[edit]
Christman studied biomedical engineering at Northwestern University. She moved to California in 2000, where she earned her graduate degrees.[citation needed] Christman was a doctoral researcher at the University of California, San Francisco (USCF), where she developed in situ approaches for myocardial tissue engineering.[3] She has said that she started working in biengineering to find a way to help patients.[4]
Research and career[edit]
After her PhD, she moved to the University of California, Los Angeles for postdoctoral research, working with Heather Maynard on polymer chemistry to develop new strategies for site-specific patterning of proteins.[5] In 2007, Christman joined the Department of Bioengineering at UCSF. She develops materials for tissue engineering and regenerative medicine. Her research considers naturally-occurring and synthetically derived hydrogels to repair and regenerate tissue.[4] She looks to use these hydrogels for non-invasive therapeutic interventions.[4] In particular, Christman has studied myocardial infarction, which is a leading cause of death worldwide and from which many people do not recover full function.[4]
In 2017, Christman was one of the most highly funded researchers at UCSF, receiving a large grant from the California Institute for Regenerative Medicine to study peripheral artery disease.[6] She is the founder of Ventrix, Inc,[7][8] which looks to create a new class of biotherapeutics that help the extracellular matrix guide the body to generate healthy tissue.[9]
Christman serves as editor-in-chief of NPG Regenerative Medicine.[10]
Awards and honors[edit]
- NIH Director's New Innovator and Transformative Research Awards[11]
- Tissue Engineering and Regenerative Medicine Society Young Investigator Award[12]
- Tissue Engineering and Regenerative Medicine Society Senior Scientist Award[12]
- Fellow of the American Institute for Medical and Biological Engineering[13]
- Fellow of the National Academy of Inventors[14]
Selected publications[edit]
Her publications[1][2] include:
- Karen L Christman; Andrew J Vardanian; Qizhi Fang; Richard E Sievers; Hubert H Fok; Randall J Lee (1 August 2004). "Injectable fibrin scaffold improves cell transplant survival, reduces infarct expansion, and induces neovasculature formation in ischemic myocardium". Journal of the American College of Cardiology. 44 (3): 654–660. doi:10.1016/J.JACC.2004.04.040. ISSN 0735-1097. PMID 15358036. Wikidata Q45206400.
- Jennifer M Singelyn; Jessica A DeQuach; Sonya B Seif-Naraghi; Robert B Littlefield; Pamela J Schup-Magoffin; Karen L Christman (15 July 2009). "Naturally derived myocardial matrix as an injectable scaffold for cardiac tissue engineering". Biomaterials. 30 (29): 5409–5416. doi:10.1016/J.BIOMATERIALS.2009.06.045. ISSN 0142-9612. PMC 2728782. PMID 19608268. Wikidata Q41969553.
- Karen L Christman; Hubert H Fok; Richard E Sievers; Qizhi Fang; Randall J Lee (1 March 2004). "Fibrin glue alone and skeletal myoblasts in a fibrin scaffold preserve cardiac function after myocardial infarction". Tissue Engineering. 10 (3–4): 403–409. doi:10.1089/107632704323061762. ISSN 1076-3279. PMID 15165457. Wikidata Q46599109.
References[edit]
- ^ a b Karen Christman publications from Europe PubMed Central
- ^ a b Karen Christman publications indexed by Google Scholar
- ^ Christman, Karen Leigh (2003). In situ engineered myocardial tissue (PhD thesis). University of California. OCLC 1023595123. ProQuest 305296067.
- ^ a b c d Talesnik, Dana (2022-03-18). "Bioengineer Develops Ways to Repair, Regenerate Tissue". NIH Record. Retrieved 2023-02-20.
- ^ Christman, Karen L.; Enriquez-Rios, Vanessa D.; Maynard, Heather D. (2006-10-17). "Nanopatterning proteins and peptides". Soft Matter. 2 (11): 928–939. doi:10.1039/B611000B. ISSN 1744-6848. PMID 32680180. S2CID 95739992.
- ^ "Karen Christman is one of the Lead Grant Recipients at UC San Diego for the 2017 Fiscal Year. | Shu Chien - Gene Lay Department of Bioengineering". bioengineering.ucsd.edu. Retrieved 2023-02-20.
- ^ "Two PhD Grads Leverage Years of Research and Startup Experience to Together Launch Ventrix Heart and Tackle Heart Failure | UCOP". www.ucop.edu. Retrieved 2023-02-20.
- ^ "About Us". Ventrix. Retrieved 2023-02-20.
- ^ "Ventrix". Ventrix. Retrieved 2023-02-20.
- ^ "About the Editors | npj Regenerative Medicine". www.nature.com. Retrieved 2023-02-20.
- ^ "NIH Director's New Innovator Award Program - 2008 Award Recipients". commonfund.nih.gov. 2018-09-18. Retrieved 2023-02-20.
- ^ a b "BME7900 Seminar Series - Karen Christman, PhD | Meinig School of Biomedical Engineering". www.bme.cornell.edu. Retrieved 2023-02-20.
- ^ "Karen Leigh Christman, Ph.D. COF-1930 - AIMBE". Retrieved 2023-02-20.
- ^ Rittenhouse, Rebekah (2023-02-14). "NAI Welcomes 95 New Emerging Innovators". NAI. Retrieved 2023-02-20.
| International | |
|---|---|
| National | |
| Academics | |
- Living people
- American bioengineers
- Women bioengineers
- 21st-century American biologists
- 21st-century American engineers
- 21st-century American women engineers
- Northwestern University alumni
- University of California, San Francisco staff
- University of California, Los Angeles staff
- University of California, San Francisco faculty
- Fellows of the American Institute for Medical and Biological Engineering
- Fellows of the National Academy of Inventors