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L-cysteate sulfo-lyase

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L-cysteate sulfo-lyase
Identifiers
EC no.4.4.1.25
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IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
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MetaCycmetabolic pathway
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The enzyme L-cysteate sulfo-lyase (EC 4.4.1.25) catalyzes the reaction

L-cysteate + H2O = hydrogensulfite + pyruvate + NH3 (overall reaction)
(1a) L-cysteate = hydrogensulfite + 2-aminoprop-2-enoate
(1b) 2-aminoprop-2-enoate = 2-iminopropanoate (spontaneous)
(1c) 2-iminopropanoate + H2O = pyruvate + NH3 (spontaneous)

This enzyme belongs to the family of lyases, specifically the class of carbon-sulfur lyases. The systematic name of this enzyme class is L-cysteate bisulfite-lyase (deaminating; pyruvate-forming). Other names in common use include L-cysteate sulfo-lyase (deaminating), and CuyA.

References

[edit]
  • Denger K, Smits TH, Cook AM (2006). "L-Cysteate sulpho-lyase, a widespread pyridoxal 5′-phosphate-coupled desulphonative enzyme purified from Silicibacter pomeroyi DSS-3(T)". Biochem. J. 394 (Pt 3): 657–64. doi:10.1042/BJ20051311. PMC 1383715. PMID 16302849.