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MARS (gene)

From Wikipedia, the free encyclopedia
MARS1
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesMARS1, METRS, MRS, MTRNS, SPG70, CMT2U, ILFS2, ILLD, methionyl-tRNA synthetase, methionyl-tRNA synthetase 1, MARS, TTD9
External IDsOMIM: 156560; MGI: 1345633; HomoloGene: 90878; GeneCards: MARS1; OMA:MARS1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_004990

NM_001003913
NM_001171582

RefSeq (protein)

NP_004981

NP_001003913
NP_001165053

Location (UCSC)Chr 12: 57.48 – 57.52 MbChr 10: 127.13 – 127.15 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Methionyl-tRNA synthetase, cytoplasmic is an enzyme that in humans is encoded by the MARS gene.[5][6]

Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. The protein encoded by this gene belongs to the class I family of tRNA synthetases.[6]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000166986Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000040354Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Ubeda M, Schmitt-Ney M, Ferrer J, Habener JF (Sep 1999). "CHOP/GADD153 and methionyl-tRNA synthetase (MetRS) genes overlap in a conserved region that controls mRNA stability". Biochem Biophys Res Commun. 262 (1): 31–8. doi:10.1006/bbrc.1999.1140. PMID 10448063.
  6. ^ a b "Entrez Gene: MARS methionyl-tRNA synthetase".

Further reading

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