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Malonyl-S-ACP decarboxylase

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Malonyl-S-ACP decarboxylase
Identifiers
EC no.4.1.1.87
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
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Malonyl-S-ACP decarboxylase (EC 4.1.1.87, malonyl-S-acyl-carrier protein decarboxylase, MdcD/MdcE, MdcD,E) is an enzyme with systematic name malonyl-(acyl-carrier-protein) carboxy-lyase.[1][2][3][4][5] This enzyme catalyses the following chemical reaction

a malonyl-[acyl-carrier protein] + H+ an acetyl-[acyl-carrier protein] + CO2

This enzyme comprises the beta and gamma subunits of the enzyme EC 4.1.1.88.

References

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  1. ^ Schmid M, Berg M, Hilbi H, Dimroth P (April 1996). "Malonate decarboxylase of Klebsiella pneumoniae catalyses the turnover of acetyl and malonyl thioester residues on a coenzyme-A-like prosthetic group". European Journal of Biochemistry. 237 (1): 221–8. doi:10.1111/j.1432-1033.1996.0221n.x. PMID 8620876.
  2. ^ Koo JH, Kim YS (December 1999). "Functional evaluation of the genes involved in malonate decarboxylation by Acinetobacter calcoaceticus". European Journal of Biochemistry. 266 (2): 683–90. doi:10.1046/j.1432-1327.1999.00924.x. PMID 10561613.
  3. ^ Handa S, Koo JH, Kim YS, Floss HG (October 1999). "Stereochemical course of biotin-independent malonate decarboxylase catalysis". Archives of Biochemistry and Biophysics. 370 (1): 93–6. doi:10.1006/abbi.1999.1369. PMID 10496981.
  4. ^ Chohnan S, Akagi K, Takamura Y (January 2003). "Functions of malonate decarboxylase subunits from Pseudomonas putida". Bioscience, Biotechnology, and Biochemistry. 67 (1): 214–7. doi:10.1271/bbb.67.214. PMID 12619701.
  5. ^ Dimroth P, Hilbi H (July 1997). "Enzymic and genetic basis for bacterial growth on malonate". Molecular Microbiology. 25 (1): 3–10. doi:10.1046/j.1365-2958.1997.4611824.x. PMID 11902724.
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