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Mitochondrial 2-oxoglutarate/malate carrier protein

From Wikipedia, the free encyclopedia

SLC25A11
Identifiers
AliasesSLC25A11, OGC, SLC20A4, solute carrier family 25 member 11, PGL6
External IDsOMIM: 604165; MGI: 1915113; HomoloGene: 2637; GeneCards: SLC25A11; OMA:SLC25A11 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_003562
NM_001165417
NM_001165418

NM_024211

RefSeq (protein)

NP_001158889
NP_001158890
NP_003553

NP_077173

Location (UCSC)Chr 17: 4.94 – 4.94 MbChr 11: 70.54 – 70.54 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Mitochondrial 2-oxoglutarate/malate carrier protein is a protein that in humans is encoded by the SLC25A11 gene.[5][6][7] Inactivating mutations in this gene predispose to metastasic paraganglioma.[8]

See also

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References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000108528Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000014606Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Piccininni S, Iacobazzi V, Lauria G, Rocchi M, Palmieri F (Mar 1999). "Assignment of the oxoglutarate carrier gene (SLC20A4) to human chromosome 17p13.3". Cytogenet Cell Genet. 83 (3–4): 256–7. doi:10.1159/000015198. PMID 10072597. S2CID 36221506.
  6. ^ Iacobazzi V, Palmieri F, Runswick MJ, Walker JE (Jan 1993). "Sequences of the human and bovine genes for the mitochondrial 2-oxoglutarate carrier". DNA Seq. 3 (2): 79–88. doi:10.3109/10425179209034000. PMID 1457818.
  7. ^ "Entrez Gene: SLC25A11 solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11".
  8. ^ Buffet A, Morin A, Castro-Vega LJ, Habarou F, Lussey-Lepoutre C, Letouzé E, Lefebvre H, Guilhem I, Magalie H (2018-02-05). "Germline mutations in the mitochondrial 2-oxoglutarate/malate carrier SLC25A11 gene confer a predisposition to metastatic paragangliomas". Cancer Research. 78 (8): 1914–1922. doi:10.1158/0008-5472.CAN-17-2463. ISSN 1538-7445. PMID 29431636.

Further reading

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