Ms1 small RNA

Ms1 sRNA
Ms1 sRNA
	Predicted secondary structure and sequence conservation of Ms1 small RNA
Identifiers
Rfam	RF02566
Other data
Domain(s)	Bacteria
GO	GO:0070063
SO	SO:0000370
PDB structures	PDBe

Mycobacterium smegmatis small RNA 1 (Ms1 small RNA) is highly expressed during stationary phase of growth, Ms1 RNA directly interacts with RNA polymerase (RNAP). but in a different way than 6S, which is present in other bacteria. Ms1 does not require the presence of the main sigma factor for RNAP interaction. There is evidence that Ms1 RNA may function similar to 6S RNA in M. smegmatis which does not have 6S RNA.^[1]

References

^ Hnilicová J, Jirát Matějčková J, Šiková M, Pospíšil J, Halada P, Pánek J, Krásný L (October 2014). "Ms1, a novel sRNA interacting with the RNA polymerase core in mycobacteria". Nucleic Acids Research. 42 (18): 11763–11776. doi:10.1093/nar/gku793. PMC 4191392. PMID 25217589.

[1] Hnilicová J, Jirát Matějčková J, Šiková M, Pospíšil J, Halada P, Pánek J, Krásný L (October 2014). "Ms1, a novel sRNA interacting with the RNA polymerase core in mycobacteria". Nucleic Acids Research. 42 (18): 11763–11776. doi:10.1093/nar/gku793. PMC 4191392. PMID 25217589.

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