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N6-hydroxylysine O-acetyltransferase

From Wikipedia, the free encyclopedia
N6-hydroxylysine O-acetyltransferase
Identifiers
EC no.2.3.1.102
CAS no.101077-53-6
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
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In enzymology, a N6-hydroxylysine O-acetyltransferase (EC 2.3.1.102) is an enzyme that catalyzes the chemical reaction

acetyl-CoA + N6-hydroxy-L-lysine CoA + N6-acetyl-N6-hydroxy-L-lysine

Thus, the two substrates of this enzyme are acetyl-CoA and N6-hydroxy-L-lysine, whereas its two products are CoA and N6-acetyl-N6-hydroxy-L-lysine.

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is acetyl-CoA:N6-hydroxy-L-lysine 6-acetyltransferase. Other names in common use include N6-hydroxylysine:acetyl CoA N6-transacetylase, N6-hydroxylysine acetylase, and acetyl-CoA:6-N-hydroxy-L-lysine 6-acetyltransferase. This enzyme participates in lysine degradation.

References

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  • Coy M, Paw BH, Bindereif A, Neilands JB (1986). "Isolation and properties of N epsilon-hydroxylysine:acetyl coenzyme A N epsilon-transacetylase from Escherichia coli pABN11". Biochemistry. 25 (9): 2485–9. doi:10.1021/bi00357a030. PMID 3521734.
  • de Lorenzo V, Bindereif A, Paw BH, Neilands JB (1986). "Aerobactin biosynthesis and transport genes of plasmid ColV-K30 in Escherichia coli K-12". J. Bacteriol. 165 (2): 570–8. doi:10.1128/jb.165.2.570-578.1986. PMC 214457. PMID 2935523.