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OSBPL3

From Wikipedia, the free encyclopedia

OSBPL3
Identifiers
AliasesOSBPL3, ORP-3, ORP3, OSBP3, oxysterol binding protein like 3
External IDsOMIM: 606732; MGI: 1918970; HomoloGene: 49422; GeneCards: OSBPL3; OMA:OSBPL3 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001163645
NM_027881
NM_001347213

RefSeq (protein)

NP_056365
NP_663160
NP_663161
NP_663162

NP_001157117
NP_001334142
NP_082157

Location (UCSC)Chr 7: 24.8 – 24.98 MbChr 6: 50.27 – 50.43 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Oxysterol-binding protein-related protein 3 is a protein that in humans is encoded by the OSBPL3 gene.[5][6]

Function

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This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain. Several transcript variants encoding different isoforms have been identified.[6]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000070882Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000029822Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Ishikawa K, Nagase T, Suyama M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (Jun 1998). "Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro". DNA Research. 5 (3): 169–76. doi:10.1093/dnares/5.3.169. PMID 9734811.
  6. ^ a b "Entrez Gene: OSBPL3 oxysterol binding protein-like 3".

Further reading

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