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Opheline kinase

From Wikipedia, the free encyclopedia
opheline kinase
Identifiers
EC no.2.7.3.7
CAS no.37278-15-2
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
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PMCarticles
PubMedarticles
NCBIproteins

In enzymology, an opheline kinase (EC 2.7.3.7) is an enzyme that catalyzes the chemical reaction

ATP + guanidinoethyl methyl phosphate ADP + N'-phosphoguanidinoethyl methylphosphate

Thus, the two substrates of this enzyme are ATP and guanidinoethyl methyl phosphate, whereas its two products are ADP and N'-phosphoguanidinoethyl methylphosphate.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with a nitrogenous group as acceptor. The systematic name of this enzyme class is ATP:guanidinoethyl-methyl-phosphate phosphotransferase.

References

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  • Thoai NV, di Jeso F, Robin Y, der Terrossian E (1966). "Sur la nouvelle acide adenosine 5'-triphosphorique:guanidine phosphotransferase, l'opheline kinase". Biochim. Biophys. Acta. 113: 542–550. doi:10.1016/s0926-6593(66)80012-7.